Intraabdominal Pressure in Critically Ill Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-11-01

Study Completion Date

2020-12-30

Brief Summary

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This study is conducted to evaluate the incidence and prognostic significance of IAH in medical ICU patients.

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Detailed Description

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Increased Intra-abdominal pressure (IAP) is an important cause of morbidity and mortality in ICU patients with consequent pulmonary, hepatic, central nervous and renal system impairments.

The increase in IAP is rarely diagnosed in ICU and the lack of diagnosis of this condition may lead to the worsening of patient prognoses because of retardation of appropriate interventions .

The current literatures show conflicting cutoff values of IAP that predict AKI, possibly due to the fact that many studies were conducted before publishing of the first Consensus of IAH/ACS, which standardized the measurement method of IAP.

Intra-abdominal hypertension is defined as a sustained or repeated pathologic elevation of intra-abdominal pressure greater than 12 mmHg \[Malbrain et al 2004, cheathamML et al 2007\]. Intra-abdominal hypertension is graded as follows:

* Grade I Intra-abdominal pressure 12-15 mmHg.
* Grade II Intra-abdominal pressure 16-20 mmHg.
* Grade III Intra-abdominal pressure 21-25 mmHg.
* Grade IV Intra-abdominal pressure greater than 25 mmHg Various risk factors contribute to the development of IAH in medical ICU including; massive fluid resuscitation (\> 3500 ml/24 h), ileus, respiratory, renal, or liver dysfunction, hypothermia, acidosis, anemia, oliguria, and hyperlactatemia .

Conditions

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Critical Illness Intra-Abdominal Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Harrahill method for measuring of intraabdominal pressure

IAP obtained by using patient own urine as the transducing medium. One clamps the Foley catheter just above the urine collection bag. The tubing is then held at a position of 30-40 cm above the symphysis pubis and the clamp is released. The IAP is indicated by the height (in cm) of the urine column from the pubic bone. The meniscus should show respiratory variations.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Exclusion Criteria

* Patients diagnosed with ESRD on dialysis.
* Patients with contraindications for internal urethral catheterization as urethral injury.
* Patients who had an obvious increase in IAP as; pregnant women and obese with body mass index (BMI) \> 32 kg/m2.

Eligible Sex

ALL

Accepts Healthy Volunteers

No