Forty Five Patients With Multiple Sclerosis Recieved Vestibular Rehabilitation and Balance Training

NCT ID: NCT03670459

Last Updated: 2018-09-13

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 45 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-12-31
• Study Completion Date: 2018-09-04

Brief Summary

Patients with multiple sclerosis (MS) might develop dizziness or vertigo as a first manifestation or during the course of the illness. Many patients with MS experience chronic or intermittent dizziness. Acute symptoms of dizziness or vertigo in MS fall into two categories; acute vestibular syndrome (AVS) and positional vertigo.

Vestibular disorder due to MS decreases whole body dynamic postural control and causes many functional limitations as limitations in ambulation, dynamic balance and trunk control and that decreases the quality of life.

Vestibular dysfunction has long been recognized as causing some of the most common symptoms in MS, true vertigo is found at presentation in up to 17% of patients, several recent reports have suggested that vestibular symptoms develop early in the disease process. Vestibular Rehabilitation has been shown to be effective in reducing symptoms and improving function for patients with vestibular disorders. The goal of vestibular rehabilitation is to promote the central nervous system compensation through exercise-based strategies.

Detailed Description

The purposes of the study were to:

• Measure the effect of Cawthorne Cooksey Exercises on trunk kinetics and velocity of gait in patient with MS.
• Measure the effect of vestibular habituation on trunk kinetics and velocity of gait in patient with MS.
• Determine which type of vestibular exercises had more effect on the rehabilitation of patients with MS Cawthorne Cooksey or vestibular habituation?
• Determine if there was a correlation between the improvement in trunk kinetics and velocity of gait in patients with MS.

Forty five patients with multiple sclerosis were selected from the Out Patient Clinics of Neurology and Internal Medicine in Kasr Al- Aini Hospitals, Out Patient Clinic of Neurology, Faculty of Physical Therapy, Cairo University and 6th of October central hospital.

The selected patients were divided into three equal groups:

• Patients in G1 will receive traditional physical therapy program (balance training) for twelve sessions; day after day
• Patients in G2 will receive Cawthorne Cooksey Exercises in addition to traditional physical therapy program for twelve sessions; day after day.
• Patients in G3 will receive vestibular habituation exercises in addition to traditional physical therapy program for twelve sessions; day after day.

Conditions

Neurologic Disorder

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: FACTORIAL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Group 1

Patients in G1 will receive traditional physical therapy program (balance exercises) for twelve sessions; day after day

Group Type: EXPERIMENTAL

Balance exercises

Intervention Type: OTHER

Weight Shift Forward and Back

Group 2

Patients in G2 will receive Cawthorne Cooksey Exercises in addition to traditional physical therapy program for twelve sessions; day after day .

Group Type: EXPERIMENTAL

Cawthorne Cooksey exercises

Intervention Type: OTHER

Eye movements and head movements

Group 3

Patients in G3 will receive vestibular habituation exercises in addition to traditional physical therapy program for twelve sessions; day after day.

Group Type: EXPERIMENTAL

Vestibular habituation exercises

Intervention Type: OTHER

Move from a sitting position to flat on the back

Interventions

Cawthorne Cooksey exercises

Eye movements and head movements

Intervention Type: OTHER

Vestibular habituation exercises

Move from a sitting position to flat on the back

Intervention Type: OTHER

Balance exercises

Weight Shift Forward and Back

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• All the Patients in this study will be referred from the neurologist and will be diagnosed as relapsing-remitting multiple sclerosis in the form of hemiparesis with muscle tone of 1,1+ modified Ashworth scale.
• The diagnosis will be confirmed by MRI or CT scan and all the patients will follow the neurological examination.
• Forty five female patients ages will range from 35-55 years.
• All selected patients with central vertigo (central vestibular disorder) according to Dix Hallpike test (Cohen, 2004)
• The Degree of disability of multiple sclerosis will be from 2 - 2.5 (according to expanded disability status scale (EDSS)) (Kaufman et al, 2000)
• All the selected patients will have grade 3 group muscle test of lower limb muscles.
• All the selected patients will have scored 27-30 in mini-mental state examination (Crum et al, 1993)
• Patients who are selected in the study will be ambulant.
• Patients will be medically stable.

Exclusion Criteria

• Patients with musculoskeletal deformity.
• Patients with diabetes mellitus.
• Patients with psychological disturbance or seizures.
• Patients with visual or impairment.
• Patients with inner ear disorders
• Patients with other neurological disorders such as cerebellar lesion

• Minimum Eligible Age: 35 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

October 6 University

OTHER

Sponsor Role: lead

Responsible Party

Hosam Magdy Metwally

Hossam.magdy.pt@o6u.edu.eg

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Hosam Magdy Metwally, Doctoral

Role: PRINCIPAL_INVESTIGATOR

October 6 University

Locations

October 6 University

Giza, , Egypt

Countries

Egypt

Other Identifiers

Identifier No. 11

Identifier Type: -

Identifier Source: org_study_id