LSFG-SKIN, Laser Speckle Flowgraphy

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

1 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-23

Study Completion Date

2019-03-02

Brief Summary

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The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.

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Detailed Description

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Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.

Conditions

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Hypertension Heart Failure Vascular Ischemia Burns Chemotherapy Effect Radiation Injuries Uveitis Scleritis Multiple Sclerosis Autonomic Neuropathy Stroke Intracranial Hemorrhages TIA Migraine Headache Pain

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Clinic Subjects

cardiology subjects, dermatology subjects, endocrine subjects, neurology subjects, psychiatry subjects, surgery subjects, ophthalmology subjects.

Group Type OTHER

laser speckle flowgraphy

Intervention Type DEVICE

blood flow state of the skin as real time two dimensional image

Interventions

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laser speckle flowgraphy

blood flow state of the skin as real time two dimensional image

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Controls

●Healthy normal control subjects ages 18-90

Cardiology Subjects

* Ages 18-90
* History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease

Dermatology Subjects

* Ages 18-90
* History of inflammatory and cancerous lesions

Endocrine Subjects

* Ages 18-90
* History of diabetes, thyroid disease

Neurology Subjects

* Ages 18-90
* History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis

Psychiatry Subjects

* Ages 18-90
* History of bipolar, schizophrenia, anxiety, depression

Surgery Subjects

* Ages 18-90
* History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures.

Ophthalmology Subjects

* Ages 18-90
* History of ocular disorders caused by hypo perfusion or inflammatory disorders

Exclusion Criteria

Controls

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Cardiology Subjects

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

3\. Dermatology Subjects
* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Endocrine Subjects

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Neurology Subjects

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Psychiatry Subjects

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Surgery Subjects

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Ophthalmology Subjects

* Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
* Angle closure glaucoma

Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes