Potential Benefits of Laser Treatment on Skin Blood Flow and Sweating in Burn Survivors

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

4 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-29

Study Completion Date

2025-03-01

Brief Summary

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The purpose of this study is to examine effects of laser therapy on blood flow and sweating responses in burn-injured skin.

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Detailed Description

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This is a longitudinal study in which the effects of laser therapy on cutaneous vascular responses and sweating of the treated areas are assessed. Specifically, burn survivors who will undergo standard of care laser therapy to treat burn-related scars will perform whole-body heating and local heating procedures prior to the initiation of laser therapy, at an intermediate point during the laser therapy regimen, and upon conclusion of the laser therapy regimen.

For this pilot investigation a placebo will not be incorporated.

Primary outcome variables will be skin blood flow and sweating responses from skin treated with laser therapy and adjacent untreated/uninjured skin.

Conditions

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Burn Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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fractional CO2 laser

Standard of care laser treatment of burn-related injuries will be performed. This protocol assesses the effects of those treatments on skin blood flow and sweating responses.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 18-65 years old
* Experience a severe burn injury that warrant laser therapy.
* Free of any significant underlying medical problems based upon a detailed medical history and physical exam

Exclusion Criteria

* Known heart disease
* Other chronic medical conditions requiring regular medical therapy including cancer, diabetes, uncontrolled hypertension, and uncontrolled hypercholesterolemia.
* Abnormality detected on routine screening suggestive of cardiac ischemia or previously undetected cardiac disease or resting left bundle branch block on screening electrocardiogram.
* Subject with a body mass index \>35 kg/m2
* Pregnant or planning to become pregnant within the subsequent 6 months.

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No