Skin Imaging With Technologies in Development

NCT ID: NCT00764920

Last Updated: 2025-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

750 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-10-31

Study Completion Date

2026-12-31

Brief Summary

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The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Detailed Description

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Normal and lesional skin will be assessed by the following imaging modalities:

1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.
2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.
3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue.
4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin.
5. Multiphoton Microscopy can provide images of structures of the skin.

Conditions

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Pigmented Skin Lesion of Uncertain Nature

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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Skin Imaging

non-invasive imaging modalities for assessment of skin

non-invasive imaging modalities for assessment of skin

Intervention Type DEVICE

skin imaging

Interventions

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non-invasive imaging modalities for assessment of skin

skin imaging

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* adult male or female 7 and older; able to carry out study instructions

Exclusion Criteria

* Younger than 7 years old
* pregnant woman
* breast feeding
Minimum Eligible Age

7 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Kristen Kelly

Professor Departments of Dermatology and Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kristen M Kelly, MD

Role: PRINCIPAL_INVESTIGATOR

Beckman Laser Institute University of California Irvine

Locations

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Beckman Laser Institute Medical Clinic

Irvine, California, United States

Site Status

Countries

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United States

Other Identifiers

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20086307

Identifier Type: -

Identifier Source: org_study_id

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