Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

NCT ID: NCT01166893

Last Updated: 2025-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-03-31

Study Completion Date

2030-02-28

Brief Summary

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According to the National Burn Repository 2007, the most common type of burn injury is a partial thickness burns. The current standard of care for partial thickness burns is two weeks of topical therapy and wound care. Burns that do not heal within two weeks undergo surgical excision and skin grafting.

Detailed Description

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Researcher can use the combination of Modulated Imaging and Laser Speckle Imaging can be used as an adjuvant to standard clinical evaluation to gauge burn wound and severity of infection. Researcher can image the burn wounds of and compare with current standard of care, clinical exam, and can use the outcomes information in terms of time to healing and treatment

Modulating Imaging is a noninvasive optical modality measure the metabolic functions of the burn wound.

Laser Speckle Imaging is a noninvasive optical modality can measure blood flow of burn wound.

Conditions

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Skin Burn Multiple

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Burn wound

Modulated Imaging and Laser Speckle Imaging

Modulated Imaging and Laser Speckle Imaging

Intervention Type DEVICE

wound healing

Interventions

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Modulated Imaging and Laser Speckle Imaging

wound healing

Intervention Type DEVICE

Other Intervention Names

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MI-LSI developed at UCI Beckman Laser Institute

Eligibility Criteria

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Inclusion Criteria

1. Male / female all age
2. Subjects is an inpatient or out patient with burn wound

Exclusion Criteria

1. Subjects cannot lied flat and still for the duration of the imaging
2. Subjects pregnant.
Minimum Eligible Age

1 Minute

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of General Medical Sciences (NIGMS)

NIH

Sponsor Role collaborator

University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Anthony Joseph Durkin

Associate Professor, Director, Laboratory for Functional Imaging and Spectroscopy of Superficial Tissues

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Anthony Durkin, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California, Irvine

Locations

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UCIMC

Orange, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Gordon Kennedy, PhD

Role: CONTACT

949-824-4713

Facility Contacts

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Victor Joe, MD

Role: primary

714-456-5840

Other Identifiers

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R01GM108634

Identifier Type: NIH

Identifier Source: secondary_id

View Link

20097322

Identifier Type: -

Identifier Source: org_study_id

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