Pupillography as Screening Tool for Brain Insulin Resistance
NCT ID: NCT03651661
Last Updated: 2019-01-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
22 participants
INTERVENTIONAL
2018-07-03
2019-01-07
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Role of Obstructive Sleep Apnea Syndrome in the Occurrence of Diabetic Retinopathy in Type 2 Diabetes.
NCT03314467
A Comparison Between Pupillometry, Heart Rate Variability and Metaiodobenzylguanidine Scintigraphy for the Diagnosis of Early Diabetic Autonomic Neuropathy in Type 1 Diabetes
NCT01822431
Effect of Glucose on Ocular Blood Flow
NCT00350129
Hippocampal Metabolism and Function in Patients With Type 1 Diabetes
NCT01852968
Measurement of Total Retinal Blood Flow and Oxygen Extraction in Patients With Diabetes and Healthy Subjects
NCT03552562
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
nasal insulin
160 U of human insulin as nasal spray
human insulin
human insulin administered as nasal spray
Pupillography
Autonomic tone will be adressed by pupillography using the F2D2 (Amtech Germany) device.
nasal placebo
placebo as nasal spray
placebo
placebo administered as nasal spray
Pupillography
Autonomic tone will be adressed by pupillography using the F2D2 (Amtech Germany) device.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
human insulin
human insulin administered as nasal spray
placebo
placebo administered as nasal spray
Pupillography
Autonomic tone will be adressed by pupillography using the F2D2 (Amtech Germany) device.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* HbA1c \<5.8%
* Age between 18 and 60 years
* written consent
Exclusion Criteria
* lactating women
* Minors or non-consenting subjects are also excluded
* Acute illness or infection within the last 4 weeks
* Neurological and psychiatric disorders
* intake of centrally acting drugs
* Subjects with hemoglobin levels Hb \<12g / dl (in females), Hb \<14g / dl (males)
* Allergic diseases against one of the substances used
18 Years
60 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University Hospital Tuebingen
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Tuebingen, Department of Internal Medicine IV
Tübingen, , Germany
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
567/20168O2
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.