Long-term Safety and Performance of the ARGOS-IO Intraocular Pressure Sensor System in Subjects With Primary Open Angle Glaucoma (POAG)

NCT ID: NCT03651336

Last Updated: 2025-05-09

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-15

Study Completion Date

2022-04-27

Brief Summary

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The purpose of this study is to evaluate the long-term safety and performance of the ARGOS-IO system in patients with Primary Open Angle Glaucoma (POAG)

Detailed Description

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This study is a prospective open-label, multicenter study for clinical follow-up of the ARGOS-01 and ARGOS-02 patients.

From the ARGOS-01 to the ARGOS-02 study, some modifications were made to the form of the ARGOS-IO implant in consequence of the outcomes of the ARGOS-01 study.

Maximal 5 patients of the ARGOS-01 study and maximal 21 patients of the ARGOS-02 study will take part in this study.

The sensor was always implanted in one eye only which will be the study eye.

Conditions

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Primary Open-angle Glaucoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Single-arm longterm follow-up ARGOS-IO Sensor Pressure System

The ARGOS-IO sensor was already implanted in a previous study as ARGOS-01 or ARGOS-02.

Group Type OTHER

ARGOS-IO Sensor Pressure System

Intervention Type DEVICE

The ARGOS-IO Pressure sensor have been additionally implanted during local routine working procedures for cataract surgery in Patients with Primary Open Angle Glaucoma (POAG) and indicated cataract surgery in previous studies ARGOS-01 and ARGOS-02

Interventions

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ARGOS-IO Sensor Pressure System

The ARGOS-IO Pressure sensor have been additionally implanted during local routine working procedures for cataract surgery in Patients with Primary Open Angle Glaucoma (POAG) and indicated cataract surgery in previous studies ARGOS-01 and ARGOS-02

Intervention Type DEVICE

Other Intervention Names

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EYEMATE-IO

Eligibility Criteria

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Inclusion Criteria

* Subjects of the ARGOS-01 and ARGOS-02 study with an implanted ARGOS-IO pressure sensor.

Exclusion Criteria

* N/A
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Implandata Ophthalmic Products GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hagen Thieme, Prof.

Role: PRINCIPAL_INVESTIGATOR

Universitätsaugenklinik Magdeburg

Locations

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Klinik für Augenheilkunde, Uniklinik RWTH Aachen

Aachen, , Germany

Site Status

Universitäts-Augenklinik Bochum

Bochum, , Germany

Site Status

Universitätsaugenklinik Magdeburg

Magdeburg, , Germany

Site Status

Universitäts-Augenklinik Tübingen

Tübingen, , Germany

Site Status

Countries

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Germany

References

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Mansouri K, Rao HL, Weinreb RN. Nyctohemeral effects of topical beta-adrenoceptor blocking agents measured with an intraocular telemetry sensor. Br J Ophthalmol. 2025 Apr 22;109(5):582-586. doi: 10.1136/bjo-2023-324760.

Reference Type DERIVED
PMID: 39510809 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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CIV-18-13-023284

Identifier Type: OTHER

Identifier Source: secondary_id

ARGOS-03

Identifier Type: -

Identifier Source: org_study_id

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