Dexmedetomidine Versus Midazolam Added to Ketamine in Pediatric Patients Undergoing Bone Marrow Aspiration and Biopsy
NCT ID: NCT03647579
Last Updated: 2019-10-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
100 participants
INTERVENTIONAL
2018-08-30
2019-04-20
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Group II : The patients will receive Dexmedetomidine intravenously (i.v.) in a dose of 2mic/kg diluted by 50ml saline over 10 minutes using syringe pump plus 1 mg/kg ketamine (iv).
The objective of this study to evaluate the clinical effects, adverse effects and recovery time of two different sedative agents (midazolam and Dexmedetomidine) combined with ketamine during conscious sedation for child patient with haematological cancer undergoing BMA \&biopsy.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children
NCT02935959
Effect of Oral Dexmedetomidine, Ketamine, Or Midazolam as Preioperative Medications.
NCT05874245
Sedation for Non-invasive Ventilation in Blunt Chest Trauma
NCT05175781
Comparing Two Doses of Midazolam With Added Dexmedetomidine for Kids Before Surgery
NCT06979791
Comparison Between Dexmeditomidine, Midazolam and Ketamine as a Sedative to Help Cannula Insertion in Pediatric Patient
NCT04704622
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
midazolam plus ketamine
midazolam intravenous infusion of 0.05 mg/kg plus 1 mg/kg ketamine
midazolam intravenously (i.v.) in a dose of 0.05 mg/kg diluted by 50ml saline over 10 minutes using syringe pump plus 1 mg/kg ketamine
dexmedetomidine plus ketamine
Dexmedetomidine intravenous infusion of 2mic/kg plus 1 mg/kg ketamine
Dexmedetomidine intravenously (i.v.) in a dose of 2mic/kg diluted by 50ml saline over 10 minutes using syringe pump plus 1 mg/kg ketamine
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
midazolam intravenous infusion of 0.05 mg/kg plus 1 mg/kg ketamine
midazolam intravenously (i.v.) in a dose of 0.05 mg/kg diluted by 50ml saline over 10 minutes using syringe pump plus 1 mg/kg ketamine
Dexmedetomidine intravenous infusion of 2mic/kg plus 1 mg/kg ketamine
Dexmedetomidine intravenously (i.v.) in a dose of 2mic/kg diluted by 50ml saline over 10 minutes using syringe pump plus 1 mg/kg ketamine
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* evidence of head injury,
* raised intracranial or intraocular tension;
* use of drugs known to interact with either study agent;
* an American Society of Anesthesiologists (ASA) physical status score greater than 2.
* Also Patients with cardiovascular, respiratory, hepatic diseases and epilepsy will be excluded.
3 Years
12 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Assiut University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Ahmed H Othman
Assisstant professor of Anesthesia ICU and pain Relief
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
South Egypt Cancer Institute, Assiut University
Asyut, , Egypt
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
17100208
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.