The Mechanism and Prognosis of Pulmonary Circulation Dysfunction

NCT ID: NCT03616366

Last Updated: 2018-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-10

Study Completion Date

2020-12-31

Brief Summary

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Venous thromboembolism (VTE) is a condition which influenced by both environmental and genetic factors. This study is going to explore new significant Single nucleotide polymorphisms (SNPs) associated with VTE by Genome-Wide Association Studies (GWAS) and bioinformatics analysis. Transcriptomics and cytokine antibody array are also used to find new biomarkers of VTE's early diagnosis, severity and prognosis.

Detailed Description

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Conditions

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VTE

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Chinese Han population older than 14 years old
* Acute VTE patients diagnosed in 1 month
* With informed consent

Exclusion Criteria

* Patients with psychosis
* Patients with contraindications for computed tomographic pulmonary angiography (CTPA)
* Chronic VTE
* Recurrence of chronic VTE
Minimum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jianguo He

Chief of Pulmonary Vascular Disease Center

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cardiovascular Institute and Fu Wai Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jianguo He, MD

Role: CONTACT

80-10-88398060

Facility Contacts

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Jianguo He, MD

Role: primary

86 01088398060

Other Identifiers

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2017-I2M-1-009

Identifier Type: -

Identifier Source: org_study_id

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