Effects of Dexmedetomidine on OI, RI and Inflammatory Factors in Patients Undergoing Palatopalatyngoplasty.
NCT ID: NCT03612440
Last Updated: 2018-08-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
80 participants
INTERVENTIONAL
2018-08-01
2019-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
TRIPLE
Study Groups
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Group D
40 patients receive a loading infusion of dexmedetomidine (1ug/kg)for 20min follow by a maintenance infusion (0.4ug/kg/h) continued until the end of the surgery
dexmedetomidine
receive a loading infusion of dexmedetomidine (1ug/kg)for 20min follow by a maintenance infusion (0.4ug/kg/h) continued until the end of the surgery
Group C
40 patients receive matching placebo (normal saline)
normal saline
receive matching placebo (equal volum of normal saline)
Interventions
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dexmedetomidine
receive a loading infusion of dexmedetomidine (1ug/kg)for 20min follow by a maintenance infusion (0.4ug/kg/h) continued until the end of the surgery
normal saline
receive matching placebo (equal volum of normal saline)
Eligibility Criteria
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Inclusion Criteria
* ASA physical status II-III
* Aged 18-65 years
* BMI 18.5-30kg/m2
Exclusion Criteria
* Atrioventricular block
* Allergic to the drugs
* Complicating pulmonary disease(including pulmonary infection,COPD, asthma and so on)
18 Years
65 Years
ALL
No
Sponsors
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General Hospital of Ningxia Medical University
OTHER
Responsible Party
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Principal Investigators
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Li Na
Role: PRINCIPAL_INVESTIGATOR
General Hospital of Ningxia Medical University
Locations
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General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China
Countries
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Central Contacts
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Li Na
Role: CONTACT
References
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Li N, Zhang Y, Yang F, Zhang H, Yu X, Lu K, Wang J, Ma H, Ni X. Effects of dexmedetomidine on oxygenation and inflammatory factors in patients undergoing uvulopalatopharyngoplasty: a prospective, randomized, placebo-controlled trial. Sleep Breath. 2023 Jun;27(3):1099-1106. doi: 10.1007/s11325-022-02711-1. Epub 2022 Sep 27.
Other Identifiers
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MHX07
Identifier Type: -
Identifier Source: org_study_id
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