Navigated Repetitive Transcranial Magnetic Stimulation in Improving Motor Rehabilitation in Participants With Brain Tumors
NCT ID: NCT03606161
Last Updated: 2025-08-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
32 participants
INTERVENTIONAL
2018-08-23
2027-12-31
Brief Summary
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Detailed Description
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I. Determine feasibility of conducting 10 sessions of navigated repetitive transcranial magnetic stimulation (nrTMS) during the post-surgical rehabilitation time period.
EXPLORATORY OBJECTIVES:
I. Explore the effects of the nrTMS training program on motor recovery. II. Explore changes in cortical activity: electroencephalographic (EEG) activity including event-related potentials (ERPs) and motor evoked potentials (MEPs) will be assessed from baseline to end of treatment (EOT).
OUTLINE:
Between 1-7 days after standard of care surgery, participants undergo 10 nrTMS sessions over 30 minutes each over 3 weeks.
After completion of study, participants are followed up at 3 months.
Conditions
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Study Design
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NA
SINGLE_GROUP
SUPPORTIVE_CARE
NONE
Study Groups
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Supportive care (nrTMS)
Between 1-7 days after standard of care surgery, participants undergo 10 nrTMS sessions over 30 minutes each over 3 weeks.
Questionnaire Administration
Ancillary studies
Transcranial Magnetic Stimulation
Undergo nrTMS
Interventions
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Questionnaire Administration
Ancillary studies
Transcranial Magnetic Stimulation
Undergo nrTMS
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Understand and read English, sign a written informed consent, and be willing to follow protocol requirements
* Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
* Motor impairment must be related to the surgical procedure or the tumor itself (in the opinion of the treating physician)
* Patients who are within 7 days of brain tumor resection associated with the motor cortex
* Eligibility for the nrTMS treatment will be based on motor ability and will be determined postoperatively by the surgeon
Exclusion Criteria
* Patients who have ever been diagnosed with bipolar disorder or schizophrenia
* Patients with a history of stroke
ALL
No
Sponsors
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National Cancer Institute (NCI)
NIH
M.D. Anderson Cancer Center
OTHER
Responsible Party
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Principal Investigators
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Sarah Prinsloo
Role: PRINCIPAL_INVESTIGATOR
M.D. Anderson Cancer Center
Locations
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M D Anderson Cancer Center
Houston, Texas, United States
Countries
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Related Links
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M D Anderson Cancer Center
Other Identifiers
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NCI-2018-01476
Identifier Type: REGISTRY
Identifier Source: secondary_id
2018-0269
Identifier Type: OTHER
Identifier Source: secondary_id
2018-0269
Identifier Type: -
Identifier Source: org_study_id
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