ConfirmMDx Assay in Multiparametric MRI (mpMRI) PIRADS Scored Lesions After a Negative MR/US Fusion Biopsy

NCT ID: NCT03597386

Last Updated: 2019-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-23

Study Completion Date

2019-01-24

Brief Summary

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The purpose of this study is to see if the ConfirmMDx assay is useful in finding prostate cancer in patients who are at increased risk for prostate cancer based on elevated PSA and prostate lesion identified on mpMRI.

Detailed Description

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Conditions

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Prostate Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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All Participants

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Prior documented elevated PSA (\> 4.0 ng/ml)
* MRI lesion based on PIRADS scoring within the past 3 years
* Completed MR/US fusion prostate biopsy with concurrent systematic biopsy for PIRADS score 2-5 with negative pathological findings completed subsequent ConfirmMDx assay (regardless of result). The most recent biopsy can be within 4 years if ConfirmMDx already completed.
* May have had prior negative biopsy sessions prior to the most recent MR/US fusion biopsy
* Must be able to stop anticoagulation/antiplatelet therapy 5-7 days prior to obtaining biopsy
* Ability to give informed consent

Exclusion Criteria

* Any metastatic cancer
* Any prostate cancer
* Active infection: urinary tract infection or prostate infection precluding prostate biopsy
* Anal stenosis or severe anal disease preventing prostate biopsy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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University of Rochester

OTHER

Sponsor Role lead

Responsible Party

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Hani Rashid

Professor, Urology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Rochester Medical Center

Rochester, New York, United States

Site Status

Countries

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United States

Other Identifiers

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71689

Identifier Type: -

Identifier Source: org_study_id

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