Skeletal Muscle Parameters of Liver Cirrhosis in Non-invasive Imaging and Outcome
NCT ID: NCT03584204
Last Updated: 2021-10-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
400 participants
OBSERVATIONAL
2018-01-01
2026-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Interventions
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imaging
computed tomography, magnetic resosnance imaging, ultrasound
Eligibility Criteria
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Inclusion Criteria
* CT scan available
Exclusion Criteria
18 Years
80 Years
ALL
No
Sponsors
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University of Roma La Sapienza
OTHER
University Hospital, Bonn
OTHER
Responsible Party
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Michael Praktiknjo
Principal Investigator
Principal Investigators
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Michael Praktiknjo, MD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Bonn
Locations
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University Hospital Bonn
Bonn, , Germany
University of Frankfurt
Frankfurt, , Germany
Sapienza University of Rome
Roma, , Italy
Countries
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Central Contacts
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Facility Contacts
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Manuela Merli, Prof.
Role: primary
References
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Praktiknjo M, Zhou T, Krusken M, Jacob T, Sprinkart AM, Nowak S, Kimmann M, Dold L, Chang J, Jansen C, Strassburg CP, Luetkens J, Weismuller TJ. Myosteatosis independently predicts transplant-free survival in patients with primary sclerosing cholangitis. Dig Liver Dis. 2023 Nov;55(11):1543-1547. doi: 10.1016/j.dld.2023.08.037. Epub 2023 Aug 14.
Faron A, Abu-Omar J, Chang J, Bohling N, Sprinkart AM, Attenberger U, Rockstroh JK, Luu AM, Jansen C, Strassburg CP, Trebicka J, Luetkens J, Praktiknjo M. Combination of Fat-Free Muscle Index and Total Spontaneous Portosystemic Shunt Area Identifies High-Risk Cirrhosis Patients. Front Med (Lausanne). 2022 Apr 12;9:831005. doi: 10.3389/fmed.2022.831005. eCollection 2022.
Queck A, Thomas D, Jansen C, Schreiber Y, Ruschenbaum S, Praktiknjo M, Schwarzkopf KM, Mucke MM, Schierwagen R, Uschner FE, Meyer C, Claria J, Zeuzem S, Geisslinger G, Trebicka J, Lange CM. Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis. PLoS One. 2019 Oct 23;14(10):e0222840. doi: 10.1371/journal.pone.0222840. eCollection 2019.
Praktiknjo M, Clees C, Pigliacelli A, Fischer S, Jansen C, Lehmann J, Pohlmann A, Lattanzi B, Krabbe VK, Strassburg CP, Arroyo V, Merli M, Meyer C, Trebicka J. Sarcopenia Is Associated With Development of Acute-on-Chronic Liver Failure in Decompensated Liver Cirrhosis Receiving Transjugular Intrahepatic Portosystemic Shunt. Clin Transl Gastroenterol. 2019 Apr;10(4):e00025. doi: 10.14309/ctg.0000000000000025.
Other Identifiers
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SLIM
Identifier Type: -
Identifier Source: org_study_id
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