Myoelectric Computer Interface to Reduce Muscle Co-activation After Stroke

NCT ID: NCT03579992

Last Updated: 2019-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Brief Summary

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This study examines whether in-lab training with a myoelectric-computer interface (MyCI) can reduce abnormal muscle co-activation after stroke.

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
Occupational Therapists were blinded to intervention group

Study Groups

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60-minute Isometric

60-min Isometric MyCI training: EMG-controlled game training for 60-minutes per session

Group Type EXPERIMENTAL

60-min isometric MyCI training

Intervention Type BEHAVIORAL

EMG-controlled in-lab training with arm restrained for 60 minutes per session

90-minute Isometric

90-min Isometric MyCI training: EMG-controlled game training for 90-minutes per session

Group Type EXPERIMENTAL

90-min isometric MyCI training

Intervention Type BEHAVIORAL

EMG-controlled in-lab training with arm restrained for 90 minutes per session

90-minute Movement

90-min movement MyCI training: EMG-controlled game training for 90-minutes per session

Group Type EXPERIMENTAL

90-min movement MyCI training

Intervention Type BEHAVIORAL

EMG-controlled in-lab training without restraint for 90 minutes per session

Interventions

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60-min isometric MyCI training

EMG-controlled in-lab training with arm restrained for 60 minutes per session

Intervention Type BEHAVIORAL

90-min isometric MyCI training

EMG-controlled in-lab training with arm restrained for 90 minutes per session

Intervention Type BEHAVIORAL

90-min movement MyCI training

EMG-controlled in-lab training without restraint for 90 minutes per session

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Stroke survivors at least 6 months after stroke onset
* Persistent moderate to severe arm impairment
* Increased arm tone

Exclusion Criteria

* Substantial impairment of vision, memory, language or concentration
* Botulinum toxin use in the affected arm
* Concomitant participation in another research study on the arm
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Northwestern University

OTHER

Sponsor Role lead

Responsible Party

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Marc Slutzky

Associate Professor of Neurology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marc Slutzky, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Northwestern University

Locations

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Northwestern University

Chicago, Illinois, United States

Site Status

Countries

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United States

References

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Mugler EM, Tomic G, Singh A, Hameed S, Lindberg EW, Gaide J, Alqadi M, Robinson E, Dalzotto K, Limoli C, Jacobson T, Lee J, Slutzky MW. Myoelectric Computer Interface Training for Reducing Co-Activation and Enhancing Arm Movement in Chronic Stroke Survivors: A Randomized Trial. Neurorehabil Neural Repair. 2019 Apr;33(4):284-295. doi: 10.1177/1545968319834903. Epub 2019 Mar 19.

Reference Type RESULT
PMID: 30888251 (View on PubMed)

Seo G, Kishta A, Mugler E, Slutzky MW, Roh J. Myoelectric interface training enables targeted reduction in abnormal muscle co-activation. J Neuroeng Rehabil. 2022 Jul 1;19(1):67. doi: 10.1186/s12984-022-01045-z.

Reference Type DERIVED
PMID: 35778757 (View on PubMed)

Other Identifiers

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STU00042554

Identifier Type: -

Identifier Source: org_study_id

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