Mother and Infant Study Cohort (MISC)-

NCT ID: NCT03578094

Last Updated: 2018-07-05

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 257 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2015-12-01
• Study Completion Date: 2018-02-20

Brief Summary

This study aims to explore breastfeeding and complementary feeding practices of mothers in the United Arab Emirates (UAE) and its relation to the early life determinants of obesity and non-communicable diseases (NCDs). This research study will follow a prospective cohort approach. Two hundred and fifty mother-infant pairs will be followed for 18 months.

The hypothesis of this research study is that exclusive breastfeeding of the infant will provide potential protective effect against cardiometabolic risk factors. This study will also hypothesize that mothers who exclusively breastfeed their newborns would experience greater postpartum weight and body fat loss than mothers who are not breastfeeding.

Detailed Description

United Arab Emirates(UAE) is facing two critical situations: high incidence of obesity and chronic diseases and suboptimal infant feeding practices as reported by the Ministry of Health in the UAE. So early identification of preventive markers of cardiometabolic risk factors in breast milk is important for developing early intervention strategies to optimize health care for individuals and communities especially in countries suffering from high rates of obesity and chronic diseases such as the UAE.

The purpose of this study is to prospectively follow up with the mothers and their infants (from 0-18months of infants age). It will explore breastfeeding and complementary feeding practices of mothers in UAE and its relation to the early life determinants of obesity and non-communicable diseases (NCDs). It will examine the components of human milk which might offer a protective benefit against obesity and its health consequences in infancy. It will also evaluate the feeding practices of the mothers and her nutritional status and relates it to their infants' growth and development.

It is expected that this research study will fill an important knowledge gap in the understanding of the feeding practices of mothers and its relation to early-life determinants of obesity and other chronic diseases in the UAE.

Conditions

Adiposity, Breast Feeding

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Pregnant women:

• Emirate nationality or Arab expatriate
• Age: 19-40 years
• Singleton pregnancy
• Within the third trimester of pregnancy (27-42 weeks of gestation)
• Free of chronic diseases (diabetes, hypertension, kidney disease, cancer, or other chronic diseases), autoimmune disorders, or infections with the human immunodeficiency virus, or hepatitis in preconception

Exclusion Criteria

• Multiple pregnancies (pregnant with two or more fetuses)
• High-risk pregnancy or pre-eclampsia
• History of chronic diseases
• Preterm (<37 weeks of gestation) or late-term (>42 weeks of gestation) infants
• Congenital diseases or any health condition that could deter breastfeeding

• Minimum Eligible Age: 19 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Al Jalila Foundation

UNKNOWN

Sponsor Role: collaborator

University of Sharjah

OTHER

Sponsor Role: lead

Responsible Party

Hadia Radwan

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Hadia Radwan, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Sharjah

Locations

Hadia Radwan

Sharjah city, Shajah, United Arab Emirates

Countries

United Arab Emirates

Other Identifiers

1501057003-P

Identifier Type: -

Identifier Source: org_study_id