Effect on Early Somatic Growth of a Daily Kinesthetic Stimulation on Preterm Infants

NCT ID: NCT03574350

Last Updated: 2018-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-08-15

Study Completion Date

2018-02-28

Brief Summary

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Kangaroo position (KP), the essential component of the Kangaroo Mother Care (KMC) method, has been increasingly implemented, given the benefits of early skin-to-skin contact on the cerebral maturation of preterm infants. In addition it allows for parents to bond with their infants and humanize the care of fragile infants in neonatal units. Evidence on kinesthetic stimulation (KS) is scarce and currently there is no available evidence on KS during the KP. KS is associated with massage in this paper

Detailed Description

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The objective is to study the impact of standardized KS delivered either in KP (KSKP) or in an incubator (KSI) on the early growth of very preterm infants.

Patients and methods: Sixty six newborns ≤32 weeks of gestational age at birth received KS delivered 3 times/day during KP or in an incubator. They were randomized when the infants were considered eligibleto initiate KMC which was part of the routine care for all newborns in the Neonatal Care Unit (NCU). The primary outcome were the weight gain (g/kg/day) between randomization, 5, and 15 days after the start of the intervention and weight at 40 weeks of gestational age (term). The secondary outcomes were the same measures according to the chronological age (days of life) of the infant at randomization.

Conditions

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Preterm Infant Growth Acceleration Neurobehavioral Manifestations

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Two interventions groups of 33 each, participated in the study. The first group received Kinesthetic Stimulation in Kangaroo Position (KSKP) and the second group received Kinesthetic Stimulation In incubator (KSI ), both of the interventions were delivered by parents during the period of hospitalization and at home when the infant was discharged from Hospital until 40 weeks of gestational age.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
The nurses who did anthropometrics measures didn't know the interventions assigned to each participant of the study, because the night shift was in charge of taking the data at 7:00 am in the mornings and the interventions were delivered in the morning shifts from 8:00 am until 5:00 pm. No interventions were delivered in the night.

Study Groups

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KS in Kangaroo Position (KSKP)

KS is performed while the infant is in Kangaroo Position using a lycra band to maintain the position.

Group Type EXPERIMENTAL

KS in Kangaroo Position

Intervention Type BEHAVIORAL

KSKP was applied daily at regular interval corresponding to the presence of parents. Our protocol is based on the Tiffany Field's protocol with some adjustments corresponding to the constraints of the hospital : the KS was applied 3 times a day and during 15 consecutive days in the hospital or at home and parents were responsible of delivering the intervention. Sunflower oil was used. During the first 5 days, parents performed KSKP with the support of the psychologist. After day 5, parents were expected to perform KSKP by themselves but could ask for help at any moment while in hospital or in the ambulatory follow-up. The KS always began approximately 60 minutes after the feed.

KS in incubator (KSI)

The infant is in the incubator, unclothed with diaper.

Group Type ACTIVE_COMPARATOR

KS in incubator

Intervention Type BEHAVIORAL

The infant is in the incubator, unclothed with diaper. Parents delivered KSI with the infant in supine position, stroking with the flats of the fingers with moderate pressure. Five 1-minute intervals, consisting of six 10-s periods of stroking, were applied to the following body regions: head, back, both legs and arms. The same process was repeated in prone position. The last part of the intervention was composed of 6 flexions of each extremity.

Interventions

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KS in Kangaroo Position

KSKP was applied daily at regular interval corresponding to the presence of parents. Our protocol is based on the Tiffany Field's protocol with some adjustments corresponding to the constraints of the hospital : the KS was applied 3 times a day and during 15 consecutive days in the hospital or at home and parents were responsible of delivering the intervention. Sunflower oil was used. During the first 5 days, parents performed KSKP with the support of the psychologist. After day 5, parents were expected to perform KSKP by themselves but could ask for help at any moment while in hospital or in the ambulatory follow-up. The KS always began approximately 60 minutes after the feed.

Intervention Type BEHAVIORAL

KS in incubator

The infant is in the incubator, unclothed with diaper. Parents delivered KSI with the infant in supine position, stroking with the flats of the fingers with moderate pressure. Five 1-minute intervals, consisting of six 10-s periods of stroking, were applied to the following body regions: head, back, both legs and arms. The same process was repeated in prone position. The last part of the intervention was composed of 6 flexions of each extremity.

Intervention Type BEHAVIORAL

Other Intervention Names

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KSKP KSI

Eligibility Criteria

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Inclusion Criteria

* Preterm infants (GA ≤33 weeks of gestation)
* Deemed clinically stable and eligible for the KMC intervention by the neonatologist were included.

Exclusion Criteria

* Infants with congenital anomalies
* Unstable during the first 15 days of life
Minimum Eligible Age

30 Weeks

Maximum Eligible Age

33 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Laval University

OTHER

Sponsor Role collaborator

Hospital Universitario San Ignacio

OTHER

Sponsor Role collaborator

Nathalie Charpak

OTHER

Sponsor Role lead

Responsible Party

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Nathalie Charpak

Dr Andrea Aldana

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Andrea C Aldana Acosta, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidad Piloto de Colombia

Locations

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Nathalie Charpak

Bogotá, Cundinamarca, Colombia

Site Status

Countries

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Colombia

References

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Field T, Diego M, Hernandez-Reif M. Potential underlying mechanisms for greater weight gain in massaged preterm infants. Infant Behav Dev. 2011 Jun;34(3):383-9. doi: 10.1016/j.infbeh.2010.12.001. Epub 2011 May 13.

Reference Type RESULT
PMID: 21570125 (View on PubMed)

Diego MA, Field T, Hernandez-Reif M. Vagal activity, gastric motility, and weight gain in massaged preterm neonates. J Pediatr. 2005 Jul;147(1):50-5. doi: 10.1016/j.jpeds.2005.02.023.

Reference Type RESULT
PMID: 16027695 (View on PubMed)

Guzzetta A, Baldini S, Bancale A, Baroncelli L, Ciucci F, Ghirri P, Putignano E, Sale A, Viegi A, Berardi N, Boldrini A, Cioni G, Maffei L. Massage accelerates brain development and the maturation of visual function. J Neurosci. 2009 May 6;29(18):6042-51. doi: 10.1523/JNEUROSCI.5548-08.2009.

Reference Type RESULT
PMID: 19420271 (View on PubMed)

Related Links

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https://www.youtube.com/watch?v=WrxDLOBiiZs

Kinesthetic stimulation in Kangaroo Position (KSKP)

Other Identifiers

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xxxxx

Identifier Type: OTHER

Identifier Source: secondary_id

KangarooF

Identifier Type: -

Identifier Source: org_study_id

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