ABO-GLYC in Type 2 Diabetes

NCT ID: NCT03568409

Last Updated: 2022-06-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

86 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-01

Study Completion Date

2021-12-31

Brief Summary

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Evaluation of the improvement of the overall glycemic control after 6 months of treatment with ABO-GLYC, as a result of reduction of HbA1c and/or post-prandial glycemic peak.

Detailed Description

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Conditions

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Type2 Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Group A: ABO-GLYC

Libramed

Group Type EXPERIMENTAL

ABO-GLYC

Intervention Type DEVICE

3 tablets twice a day, before the main meals (lunch and dinner) continuatively for 24 weeks.

Group B: Placebo

Group Type PLACEBO_COMPARATOR

ABO-GLYC Placebo

Intervention Type OTHER

3 tablets twice a day, before the main meals (lunch and dinner) continuatively for 24 weeks.

Interventions

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ABO-GLYC

3 tablets twice a day, before the main meals (lunch and dinner) continuatively for 24 weeks.

Intervention Type DEVICE

ABO-GLYC Placebo

3 tablets twice a day, before the main meals (lunch and dinner) continuatively for 24 weeks.

Intervention Type OTHER

Other Intervention Names

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Libramed

Eligibility Criteria

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Inclusion Criteria

1. Male and female patients with diagnosis of type 2 diabetes, aged 18-75
2. HbA1c at screening between 6.5% and 7.5%
3. Last 2 HbA1c values in the last 12 months between 6.5% and 7.5%
4. Intolerance to metformin without unquestionable indication to other oral hypoglycemic agents
5. BMI 25-38 kg/m2
6. Willing and able to understand and sign the informed consent and complete the patient diary provided
7. Women participant of childbearing age should be negative to pregnancy test (performed on blood), and will have to use an appropriate contraceptive method throughout the study.

Exclusion Criteria

1. Micro and macrovascular complication of diabetes in advanced stage (i.e., proliferative diabetic retinopathy; chronic renal failure III-IV stage KDOQI)
2. Chronic gastro-intestinal disease
3. Heavy smoker subjects
4. Alcohol abuse
5. Chronic liver and kidney disease (AST or ALT values \> 2.5 UNL or plasma creatinine \> 1.5 mg/dl)
6. Previous major gastrointestinal surgery
7. History of eating disorders
8. Pregnancy or lactation
9. Use of food supplements containing in particular but not limited to fibers and polysaccharides, in the last six months with frequency and dosage such as to interfere with the study.
10. Autoimmune diseases
11. Known hypersensitivity to any of the components of the product.
12. Any condition which prevent subject participation in the opinion of the principal investigator.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Latis S.r.l.

INDUSTRY

Sponsor Role collaborator

Fondazione Edmund Mach

OTHER

Sponsor Role collaborator

Aboca Spa Societa' Agricola

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Azienda Ospedaliera Padova

Padua, , Italy

Site Status

Countries

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Italy

Other Identifiers

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ABO-GLYC-16

Identifier Type: -

Identifier Source: org_study_id

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