A Study to Compare PK, PD and Safety of CKD-381 and D026 in Healthy Subjects

NCT ID: NCT03558425

Last Updated: 2018-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

41 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-27

Study Completion Date

2018-09-14

Brief Summary

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A Study to compare pharmacokinetics and safety of CKD-381 and D026 in healthy subjects

Detailed Description

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Conditions

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GERD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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TR group

Period 1: Test drug(CKD-381) Period 2: Reference drug(D026)

Group Type EXPERIMENTAL

D026

Intervention Type DRUG

1 tablet administered before the breakfast during 7 days

RT group

Period 1: Reference drug(D026) Period 2: Test drug(CKD-381)

Group Type EXPERIMENTAL

CKD-381

Intervention Type DRUG

1 tablet administered before the breakfast during 7 days

Interventions

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CKD-381

1 tablet administered before the breakfast during 7 days

Intervention Type DRUG

D026

1 tablet administered before the breakfast during 7 days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Between 19 aged and 50 aged in healthy male adult
2. Body weight more than 55kg
3. Body Mass Index more than 18.5 and under 25

Exclusion Criteria

1. Have clinically significant disease that hepatobiliary system, kidney, nervous system, immune system, respiratory system, endocrine system, hemato-oncology disease, cardiovascular system or mental illness, or a history of mental disease.
2. Have a gastrointestinal disease history that can effect drug absorption or surgery.
3. Hypersensitivity reaction or clinically significant hypersensitivity reaction in the history of Investigational product, additives or benzimidazole family.
Minimum Eligible Age

19 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Chong Kun Dang Pharmaceutical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kyung Sang Yu, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Department of Clinical Pharmacology and Therapeutics, Seoul Nat'l University College of Medicine and Hospital

Locations

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Seoul Nat'l University Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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173BE18010

Identifier Type: -

Identifier Source: org_study_id

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