Objective Verification of Physiologic Changes During Accommodation Under Binocular, Monocular, and Pinhole Conditions

NCT ID: NCT03557346

Last Updated: 2018-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-02

Study Completion Date

2017-03-31

Brief Summary

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The investigators believe that this simple, clear, and objective study may be a great help in understanding the accommodative response during various accommodative stimulation conditions.

Detailed Description

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The purpose in this study was to investigate physiological changes in accommodative power, pupil diameter, astigmatic value, and axis when visual stimuli were applied under binocular, monocular (dominant eye, non-dominant eye, ipsilateral, and contralateral), and pinhole conditions using the WAM-5500 binocular autorefractor/keratometer (Grand Seiko Co. Ltd., Hiroshima, Japan).

Conditions

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Accommodation

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Interventions

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the WAM-5500 binocular autorefractor/keratometer (Grand Seiko Co. Ltd., Hiroshima, Japan)

: Subjects underwent a basic ophthalmic examination and the accommodative response to refractive stimuli was measured. Refractive stimuli were given at 0.25 diopters (D) (4 m distance), 2D (50 cm), 3D (33 cm), and 4D (25 cm) and stimulation was applied with the eyes in binocular, monocular (dominant eye, non-dominant eye, ipsilateral, and contralateral), and pinhole conditions. In addition, changes in the astigmatic value and direction of the astigmatism axis under binocular stimulus were evaluated.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. age between 20 and 40 years
2. spherical equivalent (SE) within ± 4.0 diopters (D)
3. correctable distant and near visual acuity by glasses to 20/20
4. normal ocular alignment.

Exclusion Criteria

1. disturbance of accommodation (e.g., Adie's pupil, Parkinson's disease, accommodative esotropia, accommodative spasm, presbyopia)
2. disorders that can affect accommodation (e.g., history of ocular trauma, previous ocular surgery)
3. disorders that might limit testing accuracy (e.g., corneal pathological features, cataract, glaucoma, vitreous opacity, and retinal abnormalities).
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chung-Ang University Hosptial, Chung-Ang University College of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Hong Hyun Park

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Park H, Park IK, Shin JH, Chun YS. Objective Verification of Physiologic Changes during Accommodation under Binocular, Monocular, and Pinhole Conditions. J Korean Med Sci. 2019 Jan 21;34(4):e32. doi: 10.3346/jkms.2019.34.e32. eCollection 2019 Jan 28.

Reference Type DERIVED
PMID: 30686953 (View on PubMed)

Other Identifiers

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CAUHOphthalmology

Identifier Type: -

Identifier Source: org_study_id

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