Safety and Efficacy of the LVIS and LVIS JR Devices in the Endovascular Treatment of Intracranial Aneurysms

NCT ID: NCT03553771

Last Updated: 2024-01-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-07

Study Completion Date

2021-07-01

Brief Summary

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A French, multicenter, prospective, observational, "real life" assessment of the safety and efficacy of LVIS and LVIS JR devices in the treatment of intracranial aneurysms

Detailed Description

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This is a multicenter observational study. Treatment and follow-up visits will be done as per standard of care.

The purpose of this study is to collect data on safety of the devices used since the French reimbursement.

130 patients will be enrolled over an 18-month recruitment period. All patients will be followed for at least 12 months.

Conditions

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Intracranial Aneurysm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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LVIS and LVIS JR

Braided coil assist stents used for aneurysm embolization

Intervention Type DEVICE

Other Intervention Names

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Low Profile Visualized Intraluminal Support

Eligibility Criteria

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Inclusion Criteria

* Patient with an intracranial aneurysm for which an endovascular treatment is indicated with the device LVIS or LVIS JR, either scheduled or emergency (" Bail-out stenting ")
* Patient or patient's legally authorized representative has been informed about the study and does not oppose the collection of his/her personal data

Exclusion Criteria

* None
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Clinact

OTHER

Sponsor Role collaborator

Microvention-Terumo, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michel Piotin, MD

Role: PRINCIPAL_INVESTIGATOR

Fondation Rothschild, Paris, France

Charbel Mounayer, Prof.

Role: PRINCIPAL_INVESTIGATOR

CHU de Limoges, France

Locations

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CHU Pellgrin

Bordeaux, , France

Site Status

CHU Caen

Caen, , France

Site Status

CHU Gabriel Montpied

Clermont-Ferrand, , France

Site Status

CHU Michallon

Grenoble, , France

Site Status

Hôpital Bicêtre

Le Kremlin-Bicêtre, , France

Site Status

CHU Limoges

Limoges, , France

Site Status

Hôpital Clairval

Marseille, , France

Site Status

Hôpital de la Timone

Marseille, , France

Site Status

Hôpital Gui de Chauliac

Montpellier, , France

Site Status

Hôpital Central de Nancy

Nancy, , France

Site Status

Hôpital Pasteur 2

Nice, , France

Site Status

Hôpital Lariboisière

Paris, , France

Site Status

Hôpital Pitié-Salpêtrière

Paris, , France

Site Status

La Fondation Rothschild

Paris, , France

Site Status

Hôpital Maison Blanche

Reims, , France

Site Status

Hôpital Nord

Saint-Etienne, , France

Site Status

Hôpital Foch

Suresnes, , France

Site Status

Hôpital d'instruction des Armées Saint-Anne

Toulon, , France

Site Status

Hôpital Purpan

Toulouse, , France

Site Status

Hôpital Bretonneau

Tours, , France

Site Status

Countries

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France

References

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Forestier G, Piotin M, Chau Y, Derelle AL, Brunel H, Aggour M, Saleme S, Levrier O, Pierot L, Barreau X, Boubagra K, Janot K, Barbier C, Clarencon F, Chabert E, Spelle L, Arteaga C, Consoli A, Machi P, Blanc R, Rodesch G, Cortese J, Sourour N, Herbreteau D, Heck O, Soize S, Marnat G, Rouchaud A, Anxionnat R, Sedat J, Mounayer C; LEPI investigators. Safety and effectiveness of the LVIS and LVIS Jr devices for the treatment of intracranial aneurysms: Final results of the LEPI multicenter cohort study. J Neuroradiol. 2024 May;51(3):242-248. doi: 10.1016/j.neurad.2023.10.007. Epub 2023 Oct 17.

Reference Type DERIVED
PMID: 37858720 (View on PubMed)

Related Links

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https://pubmed.ncbi.nlm.nih.gov/37858720/

Safety and effectiveness of the LVIS and LVIS Jr devices for the treatment of intracranial aneurysms: Final results of the LEPI multicenter cohort study

Other Identifiers

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LEPI

Identifier Type: -

Identifier Source: org_study_id

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