Effects of Platelet-rich Plasma in the Surgery of Carpal Tunnel Syndrome: A Randomized Controlled Trial
NCT ID: NCT03548259
Last Updated: 2019-02-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2018-06-05
2018-11-05
Brief Summary
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Design: Randomized Controlled Trial. Setting: Local Hospital.
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Detailed Description
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The treatment of the CTS includes both, conservative and surgical treatment depending on the severity of the symptoms.
Platelet-rich plasma (PRP) has been proved to be efficient in the non-surgical treatment of CTS, however its potential used as co-adjuvant in surgical treatment has not been assessed.
We propose a randomized clinical trial in patients in which the surgical treatment is indicated. Participants in the intervention group receive a PRP injection, and in the control group a platelet-poor plasma injection after open carpal tunnel release. The evaluation is performed pretreatment as well as on the 6st week after treatment. Outcome measures include: hand grip strength (primary outcome), pain, sympton severity and functional status.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Experimental
Platelet-rich plasma
Platelet-rich plasma
Platelet-rich plasma injection
Platelet-poor plasma
Platelet-poor plasma injection
Platelet-poor plasma
Platelet-poor plasma
Platelet-rich plasma
Platelet-rich plasma injection
Platelet-poor plasma
Platelet-poor plasma injection
Interventions
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Platelet-rich plasma
Platelet-rich plasma injection
Platelet-poor plasma
Platelet-poor plasma injection
Eligibility Criteria
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Inclusion Criteria
* Conservative treatment failure
Exclusion Criteria
* Wrist fracture/trauma in history
* Polyneuropathy
* Diabetes mellitus
* Cervical neuropathy
18 Years
65 Years
ALL
No
Sponsors
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Cardenal Herrera University
OTHER
Responsible Party
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Juan F. Lisón Párraga, Dr
Head of Medicine
Principal Investigators
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Ignacio Pérez, PhD
Role: STUDY_CHAIR
Cardenal Herrera University
Locations
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Universidad CEU Cardenal Herrera
Valencia, , Spain
Countries
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Other Identifiers
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UNIVERSITY CARDENAL HERRERA-18
Identifier Type: -
Identifier Source: org_study_id
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