Effects of Task-oriented Training on Functional Mobility and Fatigue in Patients With Multiple Sclerosis

NCT ID: NCT03497468

Last Updated: 2018-04-13

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 34 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-04-30
• Study Completion Date: 2018-06-30

Brief Summary

Multiple Sclerosis (MS) is inflammatory, demyelinating and autoimmune disease of the central nervous system. It is usually seen with relapses and genetic and environmental factors play a role in the etiology. Neurological symptoms seen in MS restrict the patient's daily activity and social role participation. Mobility problems and fatigue are the most important reasons of role limitations and decreased quality of life. The importance of exercise training in disease management has been emphasized in recent years. However, few studies have investigated the effects of task-oriented trainings on symptoms of the disease. The aim of this sudy is to investigate the effects of task-oriented training additional to combined exercise training on functional capacity, mobility, balance, fatigue and quality of life in patients with MS.

Conditions

Multiple Sclerosis, Relapsing-Remitting

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Control group

Patients in this group will receive combined exercise training included aerobic and strengthening exercises, 3 times a week for 6 weeks. All exercise sessions will be performed under the supervision of a physiotherapist.

Group Type: ACTIVE_COMPARATOR

Combined exercise training

Intervention Type: OTHER

Aerobic training with cycle ergometer %60-80 of maximal Heart Rate, submaximal level, strengthening of the major muscles of upper and lower extremities

Training group

Patients in this group will receive task-oriented training additional to combined exercise training 3 times a week for 6 weeks. Task-oriented training included more functional daily life mobility activities like reaching, obstacle walking, stairs climbing. All exercise sessions will be performed under the supervision of a physiotherapist.

Group Type: EXPERIMENTAL

Task-oriented training

Intervention Type: OTHER

Functional reaching, walking on different obstacles and floor,sitting and standing on different levels and surface,walking around obstacle, climbing stairs with different height and surface

Interventions

Combined exercise training

Aerobic training with cycle ergometer %60-80 of maximal Heart Rate, submaximal level, strengthening of the major muscles of upper and lower extremities

Intervention Type: OTHER

Task-oriented training

Functional reaching, walking on different obstacles and floor,sitting and standing on different levels and surface,walking around obstacle, climbing stairs with different height and surface

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Multiple Sclerosis diagnosis
• Expanded Disability Status Scale > 5,5
• No cognitive problems
• No relapses in the last 3 months
• No other neurological or chronic disease

Exclusion Criteria

• Relapse during the intervention
• Exercise intolerance

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Bezmialem Vakif University

OTHER

Sponsor Role: lead

Responsible Party

Kamer Unal

Lecturer, PhD, PT

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Kamer Unal-Eren, PT, PhD

Role: CONTACT

kamerunals@yahoo.com

+902125232288 ext. 4650

Other Identifiers

kunal

Identifier Type: -

Identifier Source: org_study_id