Comparison of Three Lancing Devices Regarding Capillary Blood Volume and Lancing Pain Intensity.

NCT ID: NCT03479619

Last Updated: 2020-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-06

Study Completion Date

2018-09-27

Brief Summary

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A randomized single-blind study with the use of three lancing devices equipped with personal lancets. Every device will be studied for three lancet sizes: 28G, 30G, and 33G with the minimum and maximum puncture depth setting.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

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A/28/1

Lancing device A with personal lancet of size 28 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device A

Intervention Type DEVICE

Glucoject Dual Plus lancing device

28 G lancet

Intervention Type DEVICE

Droplet 28 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

A/28/5

Lancing device A with personal lancet of size 28 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device A

Intervention Type DEVICE

Glucoject Dual Plus lancing device

28 G lancet

Intervention Type DEVICE

Droplet 28 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

A/30/1

Lancing device A with personal lancet of size 30 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device A

Intervention Type DEVICE

Glucoject Dual Plus lancing device

30 G lancet

Intervention Type DEVICE

Droplet personal lancet 30 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

A/30/5

Lancing device A with personal lancet of size 30 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device A

Intervention Type DEVICE

Glucoject Dual Plus lancing device

30 G lancet

Intervention Type DEVICE

Droplet personal lancet 30 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

A/33/1

Lancing device A with personal lancet of size 33 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device A

Intervention Type DEVICE

Glucoject Dual Plus lancing device

33 G lancet

Intervention Type DEVICE

Droplet personal lancet 33 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

A/33/5

Lancing device A with personal lancet of size 33 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device A

Intervention Type DEVICE

Glucoject Dual Plus lancing device

33 G lancet

Intervention Type DEVICE

Droplet personal lancet 33 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

B/28/1

Lancing device B with personal lancet of size 28 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device B

Intervention Type DEVICE

Droplet lancing device

28 G lancet

Intervention Type DEVICE

Droplet 28 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

B/28/5

Lancing device B with personal lancet of size 28 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device B

Intervention Type DEVICE

Droplet lancing device

28 G lancet

Intervention Type DEVICE

Droplet 28 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

B/30/1

Lancing device B with personal lancet of size 30 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device B

Intervention Type DEVICE

Droplet lancing device

30 G lancet

Intervention Type DEVICE

Droplet personal lancet 30 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

B/30/5

Lancing device B with personal lancet of size 30 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device B

Intervention Type DEVICE

Droplet lancing device

30 G lancet

Intervention Type DEVICE

Droplet personal lancet 30 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

B/33/1

Lancing device B with personal lancet of size 33 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device B

Intervention Type DEVICE

Droplet lancing device

33 G lancet

Intervention Type DEVICE

Droplet personal lancet 33 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

B/33/5

Lancing device B with personal lancet of size 33 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device B

Intervention Type DEVICE

Droplet lancing device

33 G lancet

Intervention Type DEVICE

Droplet personal lancet 33 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

C/28/1

Lancing device C with personal lancet of size 28 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device C

Intervention Type DEVICE

Commercially available lancing device

28 G lancet

Intervention Type DEVICE

Droplet 28 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

C/28/5

Lancing device C with personal lancet of size 28 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device C

Intervention Type DEVICE

Commercially available lancing device

28 G lancet

Intervention Type DEVICE

Droplet 28 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

C/30/1

Lancing device C with personal lancet of size 30 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device C

Intervention Type DEVICE

Commercially available lancing device

30 G lancet

Intervention Type DEVICE

Droplet personal lancet 30 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

C/30/5

Lancing device C with personal lancet of size 30 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device C

Intervention Type DEVICE

Commercially available lancing device

30 G lancet

Intervention Type DEVICE

Droplet personal lancet 30 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

C/33/1

Lancing device C with personal lancet of size 33 G and minimum puncture depth.

Group Type EXPERIMENTAL

Lancing device C

Intervention Type DEVICE

Commercially available lancing device

33 G lancet

Intervention Type DEVICE

Droplet personal lancet 33 G

Lancing depth setting (1)

Intervention Type OTHER

The lowest depth setting (1)

C/33/5

Lancing device C with personal lancet of size 33 G and maximum puncture depth.

Group Type EXPERIMENTAL

Lancing device C

Intervention Type DEVICE

Commercially available lancing device

33 G lancet

Intervention Type DEVICE

Droplet personal lancet 33 G

Lancing depth setting (5)

Intervention Type OTHER

The highest depth setting (5)

Interventions

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Lancing device A

Glucoject Dual Plus lancing device

Intervention Type DEVICE

Lancing device B

Droplet lancing device

Intervention Type DEVICE

Lancing device C

Commercially available lancing device

Intervention Type DEVICE

28 G lancet

Droplet 28 G

Intervention Type DEVICE

30 G lancet

Droplet personal lancet 30 G

Intervention Type DEVICE

33 G lancet

Droplet personal lancet 33 G

Intervention Type DEVICE

Lancing depth setting (1)

The lowest depth setting (1)

Intervention Type OTHER

Lancing depth setting (5)

The highest depth setting (5)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with diagnosed diabetes type 1 or 2 ,
* aged 18 - 50,
* period of suffering from diabetes \>2 years,
* performing on average 3-8 daily measurements of glycaemia,
* glycaemia at the moment of the beginning of the study between 70 and 200 mg/dl.

Exclusion Criteria

* glycaemia below 70 mg/dl or glycaemia above 200 mg/dl at the moment of the beginning of the study,
* previously diagnosed hemorrhagic diathesis or heavy bleedings in the past (also those without a medical diagnosis),
* anticoagulant (thrombolytic medication) therapy within 3 weeks prior to the study or on the day of the study,
* non steroidal anti-inflammatory drugs (NSAID) treatment 1 week prior to the study or on the day of the study,
* patients with signs of dehydration,
* patients who are currently participating in another clinical study,
* currently diagnosed or reported by the patient skin diseases, nervous system diseases, psychiatric diseases, etc., which, in the opinion of the person conducting the study, disqualify the patient from the participation in the study, in care for the patient's well-being.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Lodz

OTHER

Sponsor Role collaborator

HTL-Strefa S.A.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Agnieszka Szadkowska, PhD,Md

Role: PRINCIPAL_INVESTIGATOR

Medical University of Lodz

Locations

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Nzoz Magmed

Lodz, , Poland

Site Status

Countries

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Poland

References

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Mianowska B, Mlynarski W, Szadkowska I, Szadkowska A. Evaluation of Three Lancing Devices: What Do Blood Volume and Lancing Pain Depend On? J Diabetes Sci Technol. 2021 Sep;15(5):1076-1083. doi: 10.1177/1932296820949930. Epub 2020 Aug 17.

Reference Type DERIVED
PMID: 32856497 (View on PubMed)

Other Identifiers

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010617

Identifier Type: -

Identifier Source: org_study_id

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