A Evaluation of Systematic Intensive Therapy Using CGM/FGM in Clinical Diabetes Care

NCT ID: NCT03474393

Last Updated: 2024-04-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

117 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-11-01

Study Completion Date

2023-12-31

Brief Summary

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This study aims to analyse if intensive systematic treatment via internet and telephone during 4 months improved HbA1c for persons with type 1 diabetes which are already treated with CGM or FGM, and if the effect continuous for 1-2 years after the intervention stops. Time in Hypoglycaemia, treatment satisfaction, Diabetes distress and hypoglycaemia fear will even be analysed.

A randomised, non-blinded, multi-centre, clinical study for persons with type 1 diabetes and hbA1c ≥ 58mmol/mol and treated with CGM or FGM.

The control group continuous its normal diabetes care with study visits at randomisation, 10, 18, 32, and 52 weeks for HbA1c and to fill in questionnaires.

The intervention group will have contact with the study team on a weekly basis, when mean blood glucose levels the previous week are elevated. They will receive help with analysing data and advice on how to improve their glucose values. They will even meet the study team at randomisation, 10, 18, 32, and 52 weeks for HbA1c and to fill in questionnaires.

Detailed Description

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Conditions

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Type1diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Normal diabetes care

Continue with their normal diabetes care. Come in for control visits

Group Type NO_INTERVENTION

No interventions assigned to this group

Systematic intensive therapy

Intensive Internet and telephone contact for 4 months and Control visits

Group Type EXPERIMENTAL

systematic intensive therapy

Intervention Type OTHER

intensive telephone och internet Contact with diabetes nurse for coaching and guidance over 4 months and 4 Control visits

Interventions

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systematic intensive therapy

intensive telephone och internet Contact with diabetes nurse for coaching and guidance over 4 months and 4 Control visits

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Informed consent obtained before trial-related activities (i.e., any activity that would not have been performed during routine patient management)
* Clinical diagnosis of Type 1 diabetes
* Adult patients over 18 years of age
* HbA1c ≥ 58 mmol/mol
* Currently using CGM or FGM
* To have a possibility to download and share FGM/CGM data

Exclusion Criteria

* Type 2 diabetes
* Diabetes duration \<1 year
* Long-term Systemic glucocorticoid treatment during the last 3 months
* Planned or changed treatment the last 3 months regarding MDI vs. Insulin pump or added or stopped CGM or FGM therapy
* Current or planned pregnancy or breastfeeding during the next 12 months
* Planned move during the next 12 months making it not possible to participate in study activities
* Other reason determined by the investigator not being appropriate for participation
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vastra Gotaland Region

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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NU-Hosptial Group

Uddevalla, , Sweden

Site Status

Countries

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Sweden

References

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Olafsdottir AF, Sveen KA, Wijkman M, Hallstrom S, Nilsson PH, Sterner Isaksson S, Holmer H, Ekstrom M, Imberg H, Lind M. Systematic intensive therapy in addition to continuous glucose monitoring in adults with type 1 diabetes: a multicentre, open-label, randomised controlled trial. Lancet Reg Health Eur. 2025 Oct 16;59:101485. doi: 10.1016/j.lanepe.2025.101485. eCollection 2025 Dec.

Reference Type DERIVED
PMID: 41142656 (View on PubMed)

Olafsdottir AF, Lind M. Evaluating a systematic intensive therapy using continuous glucose monitoring and intermittent scanning glucose monitoring in clinical diabetes care: a protocol for a multi-center randomized clinical trial. Front Clin Diabetes Healthc. 2023 Oct 18;4:1247616. doi: 10.3389/fcdhc.2023.1247616. eCollection 2023.

Reference Type DERIVED
PMID: 37920192 (View on PubMed)

Other Identifiers

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SIT-CGM/FGM

Identifier Type: -

Identifier Source: org_study_id

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