Evaluation of a Flash Glucose Monitoring System in Ambulatory Patients With Type 1 Diabetes

NCT ID: NCT02677454

Last Updated: 2016-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

56 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2016-04-30

Brief Summary

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To evaluate the accuracy of the Flash Glucose Monitoring system (FGM), Abbot FreeStyle Libre, used today in clinical practice in Sweden in estimating plasma glucose levels. Data will be collected in ambulatory patients with type 1 diabetes to determine safety, accuracy, and reliability.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 1 Diabetes Mellitus

Keywords

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Blood Glucose Blood Glucose Self-Monitoring

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Flash Glucose Monitor

Each patient with Type 1 diabetes will have a subcutaneous tissue FGM sensor inserted. The sensor will produce a maximum of 1440 tissue fluid glucose measurements per 24 hours and 20160 measurements during the 14 day study. The FGM data (Abbott Freestyle Libre) will be compared to the time-matched reference blood glucose measurements.

Each ambulatory patient will sample capillary blood with the HemoCue meter and measure the concentration of glucose 6 to 10 times per day for 14 days. The concentration of finger-stick capillary blood glucose will be measured using the self-monitoring blood glucose (SMBG) hemocue meter in their daily living. The subjects will record SMBG, in a written diary. Subjects will dose insulin according to their routine methods throughout the 14 day study.

Group Type EXPERIMENTAL

Flash Glucose Monitor

Intervention Type DEVICE

Interventions

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Flash Glucose Monitor

Intervention Type DEVICE

Other Intervention Names

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Abbott Freestyle Libre

Eligibility Criteria

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Inclusion Criteria

1. Type 1 diabetes
2. Adult patients, age 18 or older and \< 75 years
3. Written informed consent -

Exclusion Criteria

1. Pregnancy
2. Patients with severe cognitive dysfunction or other disease which makes FGM use difficult
3. History of allergic reaction to any of the FGMs materials or adhesives in Contact with the skin.
4. History of allergic reaction to chlorhexidine or alcohol anti-septic solution.
5. Continous Glucose Monitor (CGM) or FGM usage in the last month
6. Abnormal skin at the anticipated glucose sensor attachment sites(excessive hair, burn, inflammation, infection, rash, and/or tattoo)

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Minimum Eligible Age

18 Years

Maximum Eligible Age

74 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vastra Gotaland Region

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marcus Lind, MD, Phd

Role: PRINCIPAL_INVESTIGATOR

NU-Hospital Organization, Sweden

Locations

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NU-Hospital Group

Uddevalla, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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Libre

Identifier Type: -

Identifier Source: org_study_id