PHIL in the Treatment of Intracranial dAVF.

NCT ID: NCT03467542

Last Updated: 2024-12-31

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-24

Study Completion Date

2022-12-12

Brief Summary

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This study is a prospective, multicenter, single-arm study. Patients with Dural Arteriovenous Fistulas (dAVF) have a few choice for safe treatment. In this study, all patients with qualifying dAVFs will be treated with PHIL® Liquid Embolic material.

Detailed Description

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Conditions

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Arteriovenous Dural Fistula

Keywords

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Fistula Intracranial Dural Arteriovenous Liquid Embolic

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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dAVF treatment

PHIL® Liquid Embolic System

Group Type EXPERIMENTAL

PHIL® Liquid Embolic System

Intervention Type DEVICE

The PHIL Embolic System is indicated in the treatment of dural arteriovenous fistulas (DAVF)

Interventions

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PHIL® Liquid Embolic System

The PHIL Embolic System is indicated in the treatment of dural arteriovenous fistulas (DAVF)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age 22 - 80 years.
* Subject is willing and capable of complying with all study protocol requirements, including specified follow-up period.
* Subject or authorized legal representative must provide written informed consent prior to initiation of any study procedures.
* Subject has an intracranial dAVF

Exclusion Criteria

* Subject having multiple dAVFs to be treated.
* Subject with a history of life threatening allergy to contrast media (unless treatment for allergy is tolerated).
* Subject has known allergies to dimethylsulfoxide, iodine.
* Subject is currently participating in another clinical study
* Female subject is currently pregnant.
* Subject has co-morbid conditions that may limit survival to less than 24 months.
Minimum Eligible Age

22 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Microvention-Terumo, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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J Mocco, MD

Role: PRINCIPAL_INVESTIGATOR

Mt. Sinai

Alan Boulos, MD

Role: PRINCIPAL_INVESTIGATOR

Albany Medical College

Locations

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Albany Medical Center

Albany, New York, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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CL11005

Identifier Type: -

Identifier Source: org_study_id