EPIC US Feasibility Study: Use of the FiberNet® Emboli Protection Device in Carotid Artery Stenting

NCT ID: NCT00346515

Last Updated: 2008-10-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-06-30

Study Completion Date

2008-01-31

Brief Summary

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Multicenter, prospective, feasibility study designed to demonstrate the performance and safety of the Lumen Biomedical, Inc. FiberNet™ Embolic Protection System as an adjunctive device during carotid artery percutaneous intervention using the Guidant Acculink carotid stent in high surgical risk patients.

Detailed Description

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Conditions

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Carotid Artery Stenosis

Keywords

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carotid artery carotid stenosis carotid stenting embolic protection

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Interventions

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FiberNet Emboli Protection System

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* One or more of the high surgical risk criteria.
* Candidate for percutaneous stenting with target lesion located within common or internal carotid artery.
* Symptomatic with atherosclerotic stenosis ≥ 50% or asymptomatic with atherosclerotic stenosis ≥ 70% of the carotid artery by NASCET Criteria.

Exclusion Criteria

* Allergy to Heparin.
* Myocardial infarction within the last 14 days.
* Angioplasty or PTCA/PTA procedure within the past 48 hours.
* Cardiac surgery within the past 60 days.
* Planned invasive surgical procedure within 30 days.
* Stroke within the past 14 days.
* Transient ischemic neurological attack (TIA) or amaurosis fugax within the past 48 hours.
* Intracranial stenosis that exceeded the severity of an extracranial stenosis.
* Peripheral vascular disease of sufficient severity to prevent vascular access to the target lesion.
* Total occlusion of the target vessel.
* Lesion within 2cm of the ostium of the common carotid artery.
* A stenosis that is known to be unsuitable for stenting because of one or more of:

1. Tortuous or calcified anatomy proximal or distal to the stenosis
2. Presence of visual thrombus
3. Pseudo occlusion ('string sign')
* Serial lesions that requires more then one stent to cover entire lesion.
* Procedural complication prior to introduction of the FiberNet device into the body.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lumen Biomedical

INDUSTRY

Sponsor Role lead

Principal Investigators

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J. Michael Bacharach, MD

Role: PRINCIPAL_INVESTIGATOR

North Central Heart Institute

Locations

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Hoag Hospital

Newport Beach, California, United States

Site Status

Washington Adventist Hospital

Takoma Park, Maryland, United States

Site Status

Riverside Methodist Hospital

Columbus, Ohio, United States

Site Status

North Central Heart Institue

Sioux Falls, South Dakota, United States

Site Status

Countries

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United States

Other Identifiers

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864

Identifier Type: -

Identifier Source: org_study_id