Hydrodilatation Versus Arthroscopic Capsular Release for Frozen Shoulder

NCT ID: NCT03463538

Last Updated: 2018-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-06-30

Study Completion Date

2017-06-30

Brief Summary

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To compare the Oxford shoulder score at 6 months post intervention for primary frozen shoulder randomised to either an arthroscopic capsular release or hydro-dilatation

Detailed Description

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All potential participants for this study will be identified by an Orthopaedic Shoulder Consultant in the shoulder clinics run at the Royal Devon and Exeter NHS trust. The patients will be screened for eligibility by a research associate (SG). The eligibility criteria will be that the patient is medically fit for an operation, and has severe primary frozen shoulder in the acute painful stage, that is deemed suitable for intervention by the consultant surgeon. The patients will be informed verbally and in writing about the trial by the research associate and informed consent will be taken.

The participating patients will be randomised in a 1:1 allocation to arthroscopic capsular release (ACR) or hydrodilatation (HD). The randomisation will be administered by a central independent randomisation service, provided by a medical secretary using a computer generated randomisation sequence, who is completely independent of the trial.

All patients will be asked to fill out a number of questionnaires prior to surgery: the Oxford Shoulder Score (OSS) and the EQ-5D. The range of movement within the shoulder joint will be documented in a standard fashion.

Each patient will then undergo the assigned procedure according to the randomisation. The ACR would be performed by one of the Consultant Shoulder surgeons in their standard manner. The Hydro-dilatation would be performed by one of the Consultant Musculoskeletal radiologists in their standard manner. This would ensure that the options at each step of the operation or procedure, such as patient positioning, approach to the shoulder joint, and the closure of the wound etc are left entirely to the discretion of the Consultant performing the procedure. This will ensure that the results of the trial can be generalised to as wide a group of patients and surgeons as possible.

After the operation, patients will be reviewed using the range of movement, OSS, a patient satisfaction score and EQ-5D at 6 weeks, 3 months, and 6 months post-operatively. A record will be kept of any complications associated with the treatment. This data will be collected with by the research associate, who is independent of either intervention.

The main analysis will investigate differences in the primary outcome measure the OSS, between the two treatment groups (ACR and HD) on an intention-to-treat basis, at 6 months post-operation. Secondary outcome measures will be analysed in a similar manner. Statistical analysis will be undertaken by a statistician blinded to the interventions. Advice will be sought from an independent statistician provided by the trust to confirm the statistical methodology.

The economic evaluation will investigate the comparative cost-effectiveness of ACR versus HD. Health outcomes within 6 months follow-up will be assessed using the EuroQoL data collected within the trial, which will be valued using the standard UK TTO tariff to produce Quality-Adjusted Life-Year (QALY) estimates.

Conditions

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Frozen Shoulder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

randomised control trial between interventions
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
independent clinical reviewer of patients ROM and collection of outcome scores

Study Groups

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Arthroscopic capsular release

Surgical release performed under general anesthetic

Group Type ACTIVE_COMPARATOR

arthroscopic capsular release

Intervention Type PROCEDURE

surgical release of shoulder joint capsule

Hydro-dilatation

injection of water under local anesthetic in to shoulder joint

Group Type ACTIVE_COMPARATOR

Hydro-dilatation

Intervention Type PROCEDURE

dilatation of shoulder joint capsule using water pressure under local anesthetic

Interventions

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arthroscopic capsular release

surgical release of shoulder joint capsule

Intervention Type PROCEDURE

Hydro-dilatation

dilatation of shoulder joint capsule using water pressure under local anesthetic

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Medically fit for an operation; normal x-ray; Codmans criteria frozen shoulder

Exclusion Criteria

* Secondary causes of frozen shoulder; rotator cuff tears found at arthroscopy or hydro-dilatation; unable to adhere to trial protocol
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Royal Devon and Exeter NHS Foundation Trust

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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chris smith

Role: PRINCIPAL_INVESTIGATOR

Royal Devon and Exeter

Locations

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Royal Devon and Exeter hospital

Exeter, Devon, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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1312873

Identifier Type: -

Identifier Source: org_study_id

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