The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention

NCT ID: NCT03441997

Last Updated: 2019-01-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-02-01

Study Completion Date

2019-12-20

Brief Summary

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The purpose of this study is to compare two different exercise programs to see if there are differences after exercise in fibromyalgia (FM) symptoms and responses from the immune system.

Detailed Description

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Conditions

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Fibromyalgia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Full mind-body exercises

Participants will be trained to perform a type of mind-body exercise that involves low intensity exercise and body movements similar to Tai Chi. Participants will be asked to exercise 2 times per day for 8 weeks.

Group Type EXPERIMENTAL

Mind-body exercise

Intervention Type OTHER

Exercise program.

Light mobility exercises: Control Group

The Light mobility exercises group will perform a similar exercise as the experimental group. However without a few components. Participants will be asked to exercise two times per day for 8 weeks.

Group Type ACTIVE_COMPARATOR

Light mobility exercises

Intervention Type OTHER

Modified mind-body program.

Healthy Controls

Healthy females will be asked to make one visit to complete aerobic exercise test, questionnaires, and provide blood samples.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Mind-body exercise

Exercise program.

Intervention Type OTHER

Light mobility exercises

Modified mind-body program.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with a diagnosis of FM
* Clearance from patient's physician to participate in a clinical trial
* Not participating or willing to discontinue FM treatment with trans-cutaneous electrical nerve stimulation, biofeedback, tender-point injections, acupuncture, Yoga, and Tai Chi.


* Female
* No apparent medical condition that will interfere with participation in the study
* Not on any medication that will interfere with participation in this study

Exclusion Criteria

* Diagnosis of severe psychiatric illness
* Abuse of alcohol, benzodiazepines, or other drugs
* Active cardiovascular, pulmonary, hepatic, renal, gastrointestinal, or autoimmune disease (except Hashimoto's or Graves' disease that has been stable for 3 months before screening)
* Current systemic infection
* Active cancer (except basal cell carcinoma);
* Unstable endocrine disease
* Severe sleep apnea
* Prostate enlargement or other genitourinary disorder (male patients)
* Pregnancy or breastfeeding


* Medical or surgical conditions including medication that preclude participation in the study
* Presence of motor or neuromuscular deficits that may preclude participating in fatigue exercise
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Kansas Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Wen Liu, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Kansas Medical Center

Locations

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University of Kansas Medical Center

Kansas City, Kansas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Caio Sarmento, PT

Role: CONTACT

(913) 588-4565

Taylor Pfeifer

Role: CONTACT

(913) 588-4565

Facility Contacts

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Caio Sarmento

Role: primary

References

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Sarmento CVM, Moon S, Pfeifer T, Smirnova IV, Colgrove Y, Lai SM, Liu W. The therapeutic efficacy of Qigong exercise on the main symptoms of fibromyalgia: A pilot randomized clinical trial. Integr Med Res. 2020 Dec;9(4):100416. doi: 10.1016/j.imr.2020.100416. Epub 2020 Apr 25.

Reference Type DERIVED
PMID: 32455108 (View on PubMed)

Other Identifiers

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STUDY00141263

Identifier Type: -

Identifier Source: org_study_id

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