Nylon Versus Chromic Gut Sutures for Minor Hand Surgery

NCT ID: NCT03407820

Last Updated: 2025-07-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-31

Study Completion Date

2022-08-01

Brief Summary

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This study aims to assess the relationship between overall satisfaction with treatment in a group of randomized patients undergoing elective hand surgery using either absorbable (4-0 Chromic) or non-absorbable (5-0 Nylon) sutures. The investigators will also assess factors associated with wound concerns, pain intensity, magnitude of limitations, and physical function within one month of surgery.

Detailed Description

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Conditions

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All Minor Hand Surgery Including Carpal Tunnel Syndrome Trigger Finger Ganglion Cysts De Quervain Syndrome Dupuytren Contracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers
Both patient and surgeon will be blinded until just before the start of the procedure.

Study Groups

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1st random 50% of cohort

Absorbable Chromic gut sutures

Group Type ACTIVE_COMPARATOR

Absorbable Chromic gut sutures

Intervention Type PROCEDURE

In this group interrupted simple or horizontal mattress skin sutures are used for wound closure per surgeon preference. Standardized wound care instructions will be given to all patients. Those who received absorbable Chromic sutures are treated recording to the standard protocol and they are advised that they can start to gently rub the scab and suture line to encourage the sutures to fall off starting 10-14 days postoperatively.

2nd random 50% of cohort

Non-absorbable Nylon sutures

Group Type ACTIVE_COMPARATOR

Non-absorbable Nylon sutures

Intervention Type PROCEDURE

In this group interrupted simple or horizontal mattress skin sutures are used for wound closure per surgeon preference. Standardized wound care instructions will be given to all patients. Those who received Nylon sutures are treated recording to the standard protocol and sutures are removed after the usual time (10-14 days) of the received procedure.

Interventions

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Absorbable Chromic gut sutures

In this group interrupted simple or horizontal mattress skin sutures are used for wound closure per surgeon preference. Standardized wound care instructions will be given to all patients. Those who received absorbable Chromic sutures are treated recording to the standard protocol and they are advised that they can start to gently rub the scab and suture line to encourage the sutures to fall off starting 10-14 days postoperatively.

Intervention Type PROCEDURE

Non-absorbable Nylon sutures

In this group interrupted simple or horizontal mattress skin sutures are used for wound closure per surgeon preference. Standardized wound care instructions will be given to all patients. Those who received Nylon sutures are treated recording to the standard protocol and sutures are removed after the usual time (10-14 days) of the received procedure.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients undergoing common day-case elective hand surgery under local anesthesia, one of the following (initial) procedures:

* Carpal tunnel release
* Trigger finger release
* Ganglion excision
* Excisional biopsy
* De Quervain release
* Dupuytren fasciectomy
* Any other minor hand surgery
* Patients aged 18-89
* Able to provide informed consent
* Able to understand English or Spanish to complete questionnaires
* Patients who have an email-address or phone number (needed for follow-up)
* UT Health Austin Musculoskeletal Institute, Austin Regional Clinic, Orthopaedic Specialists of Austin.
* Available for follow-up contact after 4 weeks

Exclusion Criteria

* Patients not able to give informed consent
* Patients using corticosteroids
* Patients with one of the following comorbidities: bleeding disorder, immunodeficiency, collagen vascular disease.
* Patients known to be allergic to suture materials
* Revision procedures
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Texas at Austin

OTHER

Sponsor Role lead

Responsible Party

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David Ring

Associate Dean for Comprehensive Care. Professor of Surgery and Psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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David Ring, MD PhD

Role: PRINCIPAL_INVESTIGATOR

University of Texas at Austin

Locations

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Austin Regional Clinic

Austin, Texas, United States

Site Status

HTB Musculoskeletal Institute

Austin, Texas, United States

Site Status

Orthopedic Specialists of Austin

Austin, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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2017-11-0021

Identifier Type: -

Identifier Source: org_study_id

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