Delirium Treatment With Acupuncture in Internal Medicine Departments

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

81 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-14

Study Completion Date

2020-06-01

Brief Summary

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Delirium frequently occurs in hospitalized older people, and treatment options are limited. Acupuncture has been shown to reduce agitation in the setting of dementia. The investigators will test the hypothesis that it may also assist in treating delirium.

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Detailed Description

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This randomized-controlled trial aims to evaluate the efficacy of acupuncture integrated with standard care as compared to standard care only for the treatment of delirium in hospitalized older persons.

Patients aged 65 and older, hospitalized in the internal medicine departments of Bnai Zion Medical Center and diagnosed with delirium or subsyndromal delirium will be randomized to either true acupuncture with usual care, or usual care only. Daily treatments and outcomes' follow-up will be conducted up to one week from recruitment or until resolution of delirium or subsyndromal delirium for 48 hours. The primary outcome will be delirium resolution evaluated as time-to-first delirium remission (over 7 days) and the number of days spent delirium-free.Side effects will be monitored daily.

Conditions

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Delirium in Old Age

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Acupuncture

Acupuncture for delirium treatment

Group Type EXPERIMENTAL

Acupuncture

Intervention Type OTHER

Acupuncture added to usual care

Standard care

Standard conventional delirium care at the discretion of the department medical staff

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Acupuncture

Acupuncture added to usual care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hospitalized in internal medicine department
* Aged over 65 years
* Delirium or subsyndromal delirium within the last 48 hours

Exclusion Criteria

* Platelet count under 20x10\^9/L
* Encephalopathy explained by a cause other than delirium (acute stroke, alcohol, cirrhosis, etc.)
* History of severe dementia
* Communication barriers preventing delirium assessment

Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No