Optimizing Parameters for Long-pulsed Nd:YAG Laser for Reducing Hair Shaft Diameter

NCT ID: NCT03394235

Last Updated: 2019-01-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 14 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-02-02
• Study Completion Date: 2019-01-16

Brief Summary

This study evaluates the optimizing parameters of long pulse Nd:YAG Laser for reducing the size of hair shaft diameter of the donor for hair transplantation. All participants will receive long-pulsed Nd-YAG laser treatments with three different parameters at the occipital area.

Detailed Description

Since the beginning of hair transplantation era, hair transplant technique has been greatly improved to achieve the best natural looking of hairline and hair density. Most Asians tend to have large size of hair shaft at the donor area, which often cause unnatural look of the hairline at the frontal area after hair transplantation due to the contrast between the transplanted hair and the original hair.

The idea of reducing the size of the hair shaft in the certain part of donor area before being transplanted to the frontal hairline becomes appealing. This transection is being practiced extensively in the field of cosmetic medicine by using long-pulsed Neodymium-Doped:Yttrium Aluminum Gamet (Nd:YAG), a laser treatment for permanent hair removal and vascular lesions.

Conditions

Androgenetic Alopecia; Hair Loss/Baldness

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Long-pulsed, 1064nm Nd-YAG laser

All participants will receive long-pulsed, 1064nm Nd-YAG laser treatments with three different parameters at the occipital area.

Group Type: EXPERIMENTAL

Long-pulsed, 1064nm Nd-YAG laser

Intervention Type: DEVICE

This long-pulsed Nd-YAG laser is commonly used for laser hair removal and vascular lesions, but in this study it is used to reduce the size of the hair shaft at the occipital area.

Interventions

Long-pulsed, 1064nm Nd-YAG laser

This long-pulsed Nd-YAG laser is commonly used for laser hair removal and vascular lesions, but in this study it is used to reduce the size of the hair shaft at the occipital area.

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Men and women, aged 25-60 years with AGA or healthy
• Completed informed consent form

Exclusion Criteria

• Pregnancy or breastfeeding
• Acute infection on the scalp or any systemic infection
• Immunocompromised host
• Chronic wasting diseases
• Use of any medications which may affect hair loss such as anticoagulants, anti-hypertensive, hormones, anticonvulsants, retinoid, mood stabilizers and antidepressants
• Unstable medical problems which may affect hair loss such as thyroid diseases, autoimmune diseases, myocardial infarction, coronary bypass surgery, unstable angina, cardiac arrhythmias, congestive heart failure, cerebrovascular accident and psychiatric problems
• Hair thinning at the occipital area

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Institute of Dermatology, Thailand

OTHER_GOV

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Chinmanat Tangjaturonrusamee, MD

Role: STUDY_DIRECTOR

Institute of Dermatology

Locations

Institute of Dermatology

Bangkok, , Thailand

Countries

Thailand

Other Identifiers

007/2561

Identifier Type: -

Identifier Source: org_study_id