Treatment of Androgenetic Alopecia in Males

NCT ID: NCT00947505

Last Updated: 2012-07-30

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

49 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-08-31

Study Completion Date

2010-08-31

Brief Summary

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The purpose of this study is to evaluate the efficacy of the HairMax LaserComb 2009 7 Beam model in promoting hair growth in males diagnosed with androgenetic alopecia when treatment is applied as directed.

Detailed Description

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This is randomized, double-blind, control device clinical study across 2 sites, evaluating changes in terminal hair-count in the evaluation zone having evidence of androgenetic alopecia (miniaturized hair).

The trial will involve 45 male subjects who have been diagnosed with androgenetic alopecia, who are between 25 and 60 years of age, have Fitzpatrick Skin Types I-IV, with classifications of Norwood-Hamilton IIa to V, have active hair loss within the last 12 months.

Subjects will use the device on three nonconcurring days a week as directed per device for 26 weeks treatment duration.

Initial efficacy endpoint for each subject will be assessed at visit 4 (week 16).

Safety analysis will be assessed based on the reports of adverse events during study.

Conditions

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Androgenetic Alopecia Hair Loss Male Pattern Baldness

Keywords

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Androgenetic alopecia Hair loss Male Pattern baldness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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HairMax LaserComb 2009, 7 Beam

Lower level laser phototherapy medical device with 7 laser beams

Group Type ACTIVE_COMPARATOR

HairMax LaserComb 2009, 7 Beam

Intervention Type DEVICE

Device application 3 times week (non-consecutive days), for 26 weeks

Control Device

Identical to the Active device, but with 7 LED's instead of lasers

Group Type ACTIVE_COMPARATOR

HairMax LaserComb

Intervention Type DEVICE

Device application 3 times week (non-consecutive days), for 26 weeks

Interventions

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HairMax LaserComb 2009, 7 Beam

Device application 3 times week (non-consecutive days), for 26 weeks

Intervention Type DEVICE

HairMax LaserComb

Device application 3 times week (non-consecutive days), for 26 weeks

Intervention Type DEVICE

Other Intervention Names

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HairMax LaserComb Control device

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of androgenetic alopecia
* Fitzpatrick Skin Types I-IV
* Norwood-Hamilton IIa to V
* Active hair loss within last 12 months

Exclusion Criteria

* Photosensitivity to laser light
* Malignancy in the target area
Minimum Eligible Age

25 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Lexington International, LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael Jarratt, M.D.

Role: PRINCIPAL_INVESTIGATOR

DermaResearch, Inc.

Abe Marcadis, M.D.

Role: PRINCIPAL_INVESTIGATOR

Palm Beach Research Center

Locations

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Abe Marcadis, M.D.

Palm Beach, Florida, United States

Site Status

Michael Jarratt, MD

Austin, Texas, United States

Site Status

Countries

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United States

References

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Leavitt M, Charles G, Heyman E, Michaels D. HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia: A randomized, double-blind, sham device-controlled, multicentre trial. Clin Drug Investig. 2009;29(5):283-92. doi: 10.2165/00044011-200929050-00001.

Reference Type BACKGROUND
PMID: 19366270 (View on PubMed)

Other Identifiers

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7 2009-M-01

Identifier Type: -

Identifier Source: org_study_id