Effectiveness of Combination Therapy of Microneedling and Minoxidil in Androgenetic Alopecia of Indonesian Men
NCT ID: NCT05989165
Last Updated: 2023-09-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
36 participants
INTERVENTIONAL
2023-06-01
2023-09-15
Brief Summary
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* Is there an increase in hair density with combination therapy of microneedling and minoxidil versus minoxidil monotherapy?
* Is there an increase in hair diameter with combination therapy of microneedling and minoxidil versus minoxidil monotherapy?
Participants will be divided into 2 groups. The first one will receive minoxidil monotherapy, and the second one will receive a combination therapy of microneedling and minoxidil. Researchers will compare those 2 groups to see if there is a difference of effectiveness based on hair density and diameter.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Minoxidil 5% solution
Patients will receive minoxidil 5%, twice a day, for a total duration of 12 weeks.
Minoxidil 5% Topical Solution
Patient will be given minoxidil 5% topical solution, twice a day for 12 weeks
Combination therapy of microneedling and minoxidil 5% solution
Patients will receive a combination therapy of microneedling and minoxidil 5%. Minoxidil 5%, will be given twice a day for a total duration of 12 weeks. The microneedling treatment will be given every 4 weeks (week 0, week 4, week 8)for a total duration of 12 weeks.
Minoxidil 5% Topical Solution
Patient will be given minoxidil 5% topical solution, twice a day for 12 weeks
microneedling
Patient will be given microneedling treatment every 4 weeks
Interventions
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Minoxidil 5% Topical Solution
Patient will be given minoxidil 5% topical solution, twice a day for 12 weeks
microneedling
Patient will be given microneedling treatment every 4 weeks
Eligibility Criteria
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Inclusion Criteria
* Indonesian
* Age 18-59 years
* Diagnosis of androgenetic alopecia
* Hamilton-Norwood type III-IV
Exclusion Criteria
* Use of minoxidil or finasteride oral 1 month prior
* Skin infection in the treatment area
* Cosmetic procedures for the treatment of alopecia androgenetic such as platelet rich plasma, laser therapy,or microneedling 3 months prior
* History of keloid
18 Years
59 Years
MALE
No
Sponsors
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Indonesia University
OTHER
Responsible Party
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Kara Adistri
MD
Principal Investigators
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Kara Adistri, MD
Role: PRINCIPAL_INVESTIGATOR
Faculty of medicine, University of Indonesia
Locations
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Cipto Mangungkusumo Hospital
Jakarta, DKI Jakarta, Indonesia
Countries
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References
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Dhurat R, Sukesh M, Avhad G, Dandale A, Pal A, Pund P. A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. Int J Trichology. 2013 Jan;5(1):6-11. doi: 10.4103/0974-7753.114700.
Kumar MK, Inamadar AC, Palit A. A Randomized Controlled, Single-Observer Blinded Study to Determine the Efficacy of Topical Minoxidil plus Microneedling versus Topical Minoxidil Alone in the Treatment of Androgenetic Alopecia. J Cutan Aesthet Surg. 2018 Oct-Dec;11(4):211-216. doi: 10.4103/JCAS.JCAS_130_17.
Other Identifiers
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23030294
Identifier Type: -
Identifier Source: org_study_id
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