A Safety and Efficacy Study of PDFE-2304 Topical Solution for the Treatment of Androgenic Alopecia.

NCT ID: NCT07011485

Last Updated: 2025-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

PHASE2

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-14

Study Completion Date

2025-09-17

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study will evaluate the safety and efficacy of PDFE-2304 compared with Minoxidil 5% in men with androgenic alopecia (AGA).

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Alopecia, Androgenetic Baldness Androgenetic Alopecia (AGA)

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Parallel-group (2:1)
Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
Triple (Participant, Investigator, Outcomes Assessor)

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PDFE-2304 Topical Solution

Approximately one mL dose applied onto a pre-specified scalp area twice daily for 16 weeks.

Group Type EXPERIMENTAL

PDFE-2304 Topical Solution

Intervention Type DRUG

Approximately one mL dose applied onto a pre-specified scalp area twice daily for 16 weeks.

Minoxidil 5% Topical Solution

Approximately one mL dose applied onto a pre-specified scalp area twice daily for 16 weeks.

Group Type ACTIVE_COMPARATOR

Minoxidil 5% Topical Solution

Intervention Type DRUG

Approximately one mL dose applied onto a pre-specified scalp area twice daily for 16 weeks.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Minoxidil 5% Topical Solution

Approximately one mL dose applied onto a pre-specified scalp area twice daily for 16 weeks.

Intervention Type DRUG

PDFE-2304 Topical Solution

Approximately one mL dose applied onto a pre-specified scalp area twice daily for 16 weeks.

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Men who have a presentation of androgenetic alopecia (Norwood II - V).
* Age between 18 to 60 years of age (both inclusive).
* Have no abnormal findings during physical examination.
* Able to comply with the study procedures in the opinion of the PI/CI.
* Able to give written consent for participation in the study.

Exclusion Criteria

* Known hypersensitivity or idiosyncratic reaction to the API“s.
* Clinical diagnosis of non-AGA forms of alopecia.
* History of hair transplants.
* Subject having dyed or bleached hair 12 months prior to study start.
* Use of any topical product in the target region in the last 6 months.
* A medical history of receiving chemotherapy/cytotoxic agents.
* Uncontrolled hypertension.
* Any dermatological disorders (eczema, psoriasis, sun damage, skin cancer).
* Hormonal diseases such as thyroid disorders or diabetes.
* Liver and kidney disease.
* Smokers.
* Drug or alcohol abuse within 12 months.
* No written consent.
* The receipt of an investigational product or participation in a drug research study within a period of 90 days prior to the first dose of study drug.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

PDFE Pharma Innovations FZCO

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Koppal Institute of Medical Sciences

Koppal, Karnataka, India

Site Status

Countries

Review the countries where the study has at least one active or historical site.

India

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PDFE-CL-24-001

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.