Intraperitoneal Bupivacaine With Magnesium or Nalbuphine for Postoperative Pain Control in Laparoscopic Hysterectomy
NCT ID: NCT03393572
Last Updated: 2019-07-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
80 participants
INTERVENTIONAL
2018-01-03
2018-06-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Group BM
bupivacaine 0.25% plus magnesium sulphate.
Bupivacaine 0.25%
Patients will receive 30 mL of intraperitoneal bupivacaine 0.25%
Magnesium sulphate.
Patients will receive intraperitoneal 30 mg/kg of magnesium sulphate.
Group BN
bupivacaine 0.25% plus nalbuphine
Bupivacaine 0.25%
Patients will receive 30 mL of intraperitoneal bupivacaine 0.25%
nalbuphine
Patients will receive intraperitoneal 5 mg nalbuphine
Interventions
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Bupivacaine 0.25%
Patients will receive 30 mL of intraperitoneal bupivacaine 0.25%
Magnesium sulphate.
Patients will receive intraperitoneal 30 mg/kg of magnesium sulphate.
nalbuphine
Patients will receive intraperitoneal 5 mg nalbuphine
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* scheduled for laparoscopic hysterectomy
Exclusion Criteria
* Obesity (body mass index higher than 30 kg/ m2)
* History of chronic opioids intake
* Known hypomagnesaemia or hypermagnesaemia
* Chronic alcoholism
* Heart block
* Renal failure
* Patients with history of left ventricular failure
* Patients taking beta-blocking drugs
* Allergy to the study drugs
* if surgery changed to open hysterectomy,
20 Years
60 Years
FEMALE
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Marwa Ahmed Khairy Elbeialy
Lecturer of Anesthesia
Locations
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Marwa Elbeialy
Cairo, , Egypt
Countries
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Other Identifiers
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FMASU R49/2017
Identifier Type: -
Identifier Source: org_study_id
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