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Efficient Postoperative Pain Management With Multimodal IV

NCT ID: NCT06661746

Last Updated: 2024-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-15

Study Completion Date

2024-11-15

Brief Summary

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Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects. Epidural analgesia, though a viable option, carries its risks and complications. Recent research indicates that combining intravenous lidocaine and ketamine can significantly alleviate postoperative pain and decrease the reliance on opioids within the initial 24 hours following surgery. This approach offers a promising alternative with minimal additional adverse effects, suggesting a potential shift in pain management practices.

Detailed Description

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Conditions

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Post Operative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Multimodal Group

Group Type ACTIVE_COMPARATOR

Multimodal IV analgesia

Intervention Type DRUG

Multimodal IV analgesia of lidocaine, ketamine and MS

Epidural Group

Group Type ACTIVE_COMPARATOR

epidural analgesia

Intervention Type DRUG

Opioid-based and epidural analgesia

Interventions

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Multimodal IV analgesia

Multimodal IV analgesia of lidocaine, ketamine and MS

Intervention Type DRUG

epidural analgesia

Opioid-based and epidural analgesia

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients were assigned for surgical intervention;
* Patients of ASA grade I-III;

Exclusion Criteria

* Patients who are not in ASA grade I-III;
* Patients who had uncontrolled hypertension and/or diabetes mellitus;
* Patients who had uncompensated cardiac, renal, or hepatic diseases;
* Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs;
* Patients who refused to sign the informed consent were excluded from the study.
Minimum Eligible Age

35 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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Eman M Elafifi

Lecturer of Anesthesia, Pain & ICU

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Benha University

Banhā, El Qalyoubia, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Rc 1-7-2024

Identifier Type: -

Identifier Source: org_study_id