Conjoined Twins: a Report of Four Cases.

NCT ID: NCT03388684

Last Updated: 2024-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

4 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-02-29

Study Completion Date

2017-10-31

Brief Summary

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The present study aims to report our experience in conjoined twin separation surgery in Assuit university and pediatric hospital, Assiut university, Assiut, Egypt over a period of 20 years.

Detailed Description

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A conjoined twin is a subset of monozygotic twin gestation. It's a rare phenomenon with an incidence of 1 in 50,000 to 1:100,000 births with the higher incidence in Africa and Southwest Asia. Based on the terminology proposed by Spencer and colleagues, conjoined twins are classified according to the most prominent site of conjunction into three major groups; First, twins with a ventral union; \[cephalopagus (head), thoracopagus (Thorax), omphalopagus (Abdomen) and ischiopagus (pelvis)\]. Second; twins with a dorsal union; \[pygopagus (sacrum), rachipagus (spine, back) and craniopagus (cranium)\] and lastly; twins with a lateral union that is referred to as parapagus (side). Depending on the aspect of the embryonic disc, the most common types are thoracopagus (19%).

Surgical separation of conjoined twins is extremely challenging taking in consideration the high perioperative risk. The low incidence of such surgeries and anatomical variations in each type of conjoined twins makes each separation surgery a unique experience.

Conditions

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Conjoined Twin

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Conjoined twin separation surgery

This study included 4 case reports on conjoined twins (CT), 2 male and three female patients; 3 of them were parasitic and one was conjoined. We operated upon 2 parasitic and one conjoined. The 1st case died preoperatively.

Intervention Type PROCEDURE

Other Intervention Names

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CT Separation

Eligibility Criteria

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Inclusion Criteria

* conjoined twins
* symmetrical or
* asymmetrical.

Exclusion Criteria

* conjoined twins incompatible with life
* conjoined twins with decapitating medical illness.
Minimum Eligible Age

1 Day

Maximum Eligible Age

30 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Hala Saad Abdel-Ghaffar

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hala S Abdelghaffar, MD

Role: PRINCIPAL_INVESTIGATOR

Professor in anesthesia and intensive care department, faculty of medicine, Assiut university, Egypt.

References

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Takrouney MH, Ibrahim IA, Abdel-Ghaffar HS, Abdel-Wahhab AI, Mostafa MM, Ali WN, Abd-Elaal MS. Conjoined twins: A report of four cases. Int J Surg Case Rep. 2020;73:289-293. doi: 10.1016/j.ijscr.2020.06.072. Epub 2020 Jun 20.

Reference Type DERIVED
PMID: 32721891 (View on PubMed)

Other Identifiers

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17300170

Identifier Type: -

Identifier Source: org_study_id

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