Propellers Flaps for Meningomylocele Defects

NCT ID: NCT05188300

Last Updated: 2022-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2021-11-01

Brief Summary

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To evaluate reliability of free style propeller perforator flap for coverage MMC soft tissue defect follow a well-established step that overcome the usual problem of pedicled perforators propellers flaps.

Detailed Description

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Meningomyelocele is a serious congenital birth defect that not only affect mortality and morbidity of neonate but also a lifelong health problem.

The estimated incidence of spina bifida is 1-2 cases per 1000 population. Meningomylocele soft tissue defect reconstruction is considered a lifesaving procedure , the ideal coverage technique should be time limited , reliable and allow healing line to be away from repair of the dura . all of these criteria are available in the selection of free style propeller perforator flap as a method of reconstruction.

Conditions

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Meningocele Meningomyelocele

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Dorsal intercostal artery (DICA) perforator flaps

Retrograde dissection of free style perforator arising from DICA according to region of dorsal spine and identification of paraspinal muscle where perforator vessel was found

Group Type EXPERIMENTAL

Freestyle pedicled perforators propellers flaps for meningomyelocele defects

Intervention Type PROCEDURE

Freestyle pedicled perforators propellers flaps for meningomyelocele defects reconstruction with sequential advance in perforators dissection, large number cases, and detailed successful technique.

Trapezius musculocutaneous perforator flaps

Retrograde dissection of a free style perforator arising as a trapezius myocutenous perforator where the trapezius muscle is identified and a perforator vessel was isolated.

Group Type EXPERIMENTAL

Freestyle pedicled perforators propellers flaps for meningomyelocele defects

Intervention Type PROCEDURE

Freestyle pedicled perforators propellers flaps for meningomyelocele defects reconstruction with sequential advance in perforators dissection, large number cases, and detailed successful technique.

Lumbar artery perforators flaps

Retrograde dissection of free style perforator arising from lumbar artery according to region of lumbar spine and identification of lumbar fascia where perforator vessel was found

Group Type EXPERIMENTAL

Freestyle pedicled perforators propellers flaps for meningomyelocele defects

Intervention Type PROCEDURE

Freestyle pedicled perforators propellers flaps for meningomyelocele defects reconstruction with sequential advance in perforators dissection, large number cases, and detailed successful technique.

Interventions

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Freestyle pedicled perforators propellers flaps for meningomyelocele defects

Freestyle pedicled perforators propellers flaps for meningomyelocele defects reconstruction with sequential advance in perforators dissection, large number cases, and detailed successful technique.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All cases with dorsolumbar meningomyelocele and age up to 6 months

Exclusion Criteria

* Infants older than 6 months
* concomitant congenital anomalies
* concomitant spinal kyphosis
Minimum Eligible Age

1 Day

Maximum Eligible Age

6 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Abdel-Tawab Mohamed

Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamed K Kamel

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Awni M Shawkat, MD

Role: STUDY_CHAIR

Assiut University

Mahmoud A Mohamed

Role: STUDY_DIRECTOR

Assiut University

Locations

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Mohamed Abdeltawab

Asyut, , Egypt

Site Status

Countries

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Egypt

References

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Kushida-Contreras BH, Gaxiola-Garcia MA. Myelomeningocele defect reconstruction with keystone flaps: vascular rationale for the design and operative technique. Arch Plast Surg. 2021 May;48(3):254-260. doi: 10.5999/aps.2020.01746. Epub 2021 May 15.

Reference Type BACKGROUND
PMID: 34024069 (View on PubMed)

Formentin C, de Andrade EJ, Matias LG, Joaquim AF, Tedeschi H, Raposo-Amaral CE, Ghizoni E. Using the keystone design perforator island flap in large myelomeningocele closure. Neurosurg Focus. 2019 Oct 1;47(4):E19. doi: 10.3171/2019.7.FOCUS19383.

Reference Type BACKGROUND
PMID: 31574473 (View on PubMed)

Kesan K, Kothari P, Gupta R, Gupta A, Karkera P, Ranjan R, Mutkhedkar K, Sandlas G. Closure of large meningomyelocele wound defects with subcutaneous based pedicle flap with bilateral V-Y advancement: our experience and review of literature. Eur J Pediatr Surg. 2015 Apr;25(2):189-94. doi: 10.1055/s-0034-1368796. Epub 2014 Mar 28.

Reference Type BACKGROUND
PMID: 24683103 (View on PubMed)

Other Identifiers

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propellers flap

Identifier Type: -

Identifier Source: org_study_id

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