A Study to Assess Persistence, Adherence and Changes in Disease Activity in the Children Population of Juvenile Arthritis Patients Treated With Adalimumab (HUMIRA®)

NCT ID: NCT03383263

Last Updated: 2021-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-05-04

Study Completion Date

2020-09-14

Brief Summary

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The objective of this study is to assess persistence, adherence and changes in disease activity in the children population of juvenile arthritis patients treated with adalimumab (HUMIRA®) in the routine clinical settings in the Russian Federation.

Detailed Description

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Conditions

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Polyarticular Juvenile Arthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Children with juvenile arthritis

Children with diagnosed polyarticular juvenile arthritis according to International League of Associations for Rheumatology (ILAR) criteria treated with HUMIRA (adalimumab) in the routine clinical settings in the Russian Federation

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Confirmed diagnosis of polyarticular Juvenile Idiopathic Arthritis (JIA) according to International League of Associations for Rheumatology (ILAR) criteria .
* Planned treatment with HUMIRA according to the local product label and prescription guidelines. Alternatively, subjects assigned to HUMIRA treatment not more than 1 month prior to inclusion can be enrolled.
* Negative result of tuberculosis (TB) screening procedure and TB specialist permission to start biologic therapy.
* Patient's informed consent form signed by the parent or guardian/and by the child, if applicable.

Exclusion Criteria

* Has contraindications for the treatment with HUMIRA according to the latest version of the locally approved label.
* Any biologic drugs taken prior to 3 months of enrolment in the study.
* Patients treated with any biosimilar version of HUMIRA
* Previous participation and dropout from this study.
* Patients participating in another clinical and/or observational study priory 3 months before the enrolment to this study.
Minimum Eligible Age

2 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AbbVie

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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AbbVie Inc.

Role: STUDY_DIRECTOR

AbbVie

Locations

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Republican Children's Clinical Hospital /ID# 204830

Ufa, Bashkortostan Republic, Russia

Site Status

Chelyabinsk Regional Children's Clinical Hospital /ID# 204829

Chelyabinsk, Chelyabinsk Oblast, Russia

Site Status

Saratov State Medical University n.a. V.I. Razumovskiy /ID# 206319

Saratov, Saratov Oblast, Russia

Site Status

Kazan State Medical Academy /ID# 207004

Kazan', , Russia

Site Status

Morozovskaya Children's City Clinical Hospital /ID# 207006

Moscow, , Russia

Site Status

Sechenov First Moscow Medical /ID# 207005

Moscow, , Russia

Site Status

State Budgetary Healthcare Institution Moscow Region "Moscow Regional Consultati /ID# 212874

Mytischi, , Russia

Site Status

GBUZ NO Regional Children's Clinical Hospital /ID# 212362

Nizhny Novgorod, , Russia

Site Status

Privolzhsky Federal Medical Research Center /ID# 206318

Nizhny Novgorod, , Russia

Site Status

Regional Children's Clinical Hospital /ID# 206121

Orenburg, , Russia

Site Status

Saint Petersburg State Pediatric Medical University /ID# 203169

Saint Petersburg, , Russia

Site Status

Samara Regional Clinical Cardiology Clinic /ID# 206120

Samara, , Russia

Site Status

Federal State Budgetary Educational Institution of Higher Education National Re /ID# 212361

Saransk, , Russia

Site Status

State Budgetary Health Institution "Regional Children's Clinical Hospital №1" /ID# 212363

Yekaterinburg, , Russia

Site Status

Countries

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Russia

Related Links

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Other Identifiers

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P17-164

Identifier Type: -

Identifier Source: org_study_id

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