Development and Validation of a Preoperative Frailty Index Using Health Administrative Data

NCT ID: NCT03354546

Last Updated: 2024-09-23

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

511285 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-04-01

Study Completion Date

2016-03-31

Brief Summary

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The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Detailed Description

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The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Once derived the index will be tested to measure its association with outcomes, as well as its discrimination. Various representations of the frailty index will be tested (primary-as a continuous measure; secondary as a binary, categorical and fractional polynomial variable). Performance in subgroups will also be evaluated,

Conditions

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Frail Elderly Syndrome Surgery Outcomes Predictive Value of Tests

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Elective noncardiac surgery

Individuals having major noncardiac surgery following an elective hospital admission

Frailty index

Intervention Type DIAGNOSTIC_TEST

A frailty index composed of variables from health administrative data that cover multi-system health issues. Deficits will be coded as present or absent, and the number of deficits present will be divided by the total number of deficits present to provide an overall score between 0-1.

Emergency general surgery

Individuals having general surgery following an urgent hospital admission

Frailty index

Intervention Type DIAGNOSTIC_TEST

A frailty index composed of variables from health administrative data that cover multi-system health issues. Deficits will be coded as present or absent, and the number of deficits present will be divided by the total number of deficits present to provide an overall score between 0-1.

Interventions

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Frailty index

A frailty index composed of variables from health administrative data that cover multi-system health issues. Deficits will be coded as present or absent, and the number of deficits present will be divided by the total number of deficits present to provide an overall score between 0-1.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Having elective or emergency noncardiac surgery

Exclusion Criteria

* no provincial health insurance number
Minimum Eligible Age

66 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ottawa Hospital Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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DM8

Identifier Type: -

Identifier Source: org_study_id

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