Cardiovascular Risk Markers in Spinal Cord Injured Subjects of the Wheelchair Dancer Study

NCT ID: NCT03352505

Last Updated: 2021-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

54 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-01

Study Completion Date

2021-01-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The present study will analyze if exercise is able to elicit the well-known anti-atherogenic effects in patients with SCI. This will be evaluated by measuring vascular parameters such as endothelial and inflammatory blood markers, echocardiography of the heart and peripheral vessels, as well as blood pressure and arterial stiffness, in subjects performing either wheelchair dancing, wheelchair marathon or no sports. Further, it will be investigated, whether there is an association between neuroplasticity and cardiovascular health, as measured by electroencephalography (EEG), transcranial magnetic stimulation (TMS) and blood levels of the brain-derived neurotrophic factor (BDNF).

We hypothesize that the cardiovascular, physical and psychological benefits of wheelchair dancing and/or wheelchair marathon parallel improved neuroplasticity in SCI-patients

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

SCI - Spinal Cord Injury Cardiovascular Risk Factor

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

control

healthy walking control participants

No interventions assigned to this group

wheelchair dancer

wheelchair users, who are performing wheelchair dancing

No interventions assigned to this group

wheelchair marathon participants

wheelchair users, who are participants in wheelchair/ handbike Marathon competitions

No interventions assigned to this group

sedentary wheelchair patients

wheelchair users, who conduct exercise bouts less than 2 times per month

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

wheelchair users independent of the cause of the walking impairment, preferably with spinal cord injury.

Exclusion Criteria

metallic implanters, additional neurologic pathologies, pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Paracelsus Medical University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Prof. Josef Niebauer M.D., Ph.D., MBA

Prof. Josef Niebauer, M.D., Ph.D, MBA

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University Salzburg

Salzburg, , Austria

Site Status

Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University

Salzburg, , Austria

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Austria

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

UISM-12

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Spinal Cord Stimulation and Training
NCT05472584 RECRUITING NA
Arm and Leg Cycling for Accelerated Recovery From SCI
NCT05619146 ACTIVE_NOT_RECRUITING NA
Wheelchair Indoors Curling With SCI patients_RCT
NCT02550834 COMPLETED PHASE1/PHASE2