Cardiovascular Disease Cohort in Guangdong Province

NCT ID: NCT03351907

Last Updated: 2022-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-11-01

Study Completion Date

2030-12-31

Brief Summary

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Patients with cardiovascular diseases from Guangdong province will be recruited and followed up for at least 4 years to evaluate the risk factors for cardiovascular-related mortality and disability. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of all-cause and cardiovascular mortality will be investigated during follow-up.

Detailed Description

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5,000 patients (30-85 years old) with primary hypertension, coronary heart disease, heart failure or peripheral vascular disease and who have been living in Guangdong province for more than 5 years will be recruited. All participants will be prospectively followed up for the incidence of all-cause and cardiovascular mortality. Information about socio-demographic, diet, lifestyle, psychological status, medical history and current medication will be collected by questionnaires. Physical examinations including height, weight, waist and hip circumferences, blood pressure, fat mass and vital capacity will be conducted.Besides, blood, urine and fecal samples will be collected for further analysis. The associations between diet and lifestyle and risks for cardiovascular disease will be evaluated.

Conditions

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Cardiovascular Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Cardiovascular disease patients (30-85 years old) who have been living in Guangdong province for more than 5 years.
* Patients have been diagnosed with primary hypertension, coronary heart disease, heart failure or peripheral vascular disease, etc.

Exclusion Criteria

* Patients with cardiogenic (acute pericarditis, rheumatic coronary arteritis, hypertrophic cardiomyopathy, etc.) Or non-cardiogenic chest pain.
* any subject who suffer from malignant tumors, infectious diseases, advanced liver disease, major disability and cannot participate in the study.
Minimum Eligible Age

30 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Min Xia

OTHER

Sponsor Role lead

Responsible Party

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Min Xia

Professer

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Min Xia

Role: PRINCIPAL_INVESTIGATOR

School of Public Health,Nutrition and Food Hygiene,Sun Yat-sen University

Locations

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Sun Yat-Sen University

Guangzhou, Guangdong, China

Site Status

Countries

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China

References

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Li X, Lin Y, Wang S, Zhou S, Ju J, Wang X, Chen Y, Xia M. Extracellular Superoxide Dismutase Is Associated With Left Ventricular Geometry and Heart Failure in Patients With Cardiovascular Disease. J Am Heart Assoc. 2020 Aug 4;9(15):e016862. doi: 10.1161/JAHA.120.016862. Epub 2020 Jul 29.

Reference Type DERIVED
PMID: 32750295 (View on PubMed)

Other Identifiers

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2017XXG1120

Identifier Type: -

Identifier Source: org_study_id

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