Postoperative Periprosthetic Fractures in Hip Fracture Patients: Exeter vs Anatomic SP2 Lubinus Stem

NCT ID: NCT03326271

Last Updated: 2019-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2527 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-04

Study Completion Date

2017-10-11

Brief Summary

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Recent studies have indicated a high incidence of postoperative periprosthetic femoral fracture in elderly patients treated with two commonly used cemented polished, tapered femoral stems. The aim of this study was to compare the prevalence and incidence rate of PPF in a cohort of elderly with femoral neck fractures (FNF) treated with either a collarless, polished, tapered stem (Exeter) or an anatomic matte stem (Lubinus SP 2).

Patients and Methods In a multicentre retrospective cohort study 2529 patients 60 years and above, with a FNF as indication for primary surgery with a cemented hip arthroplasty were included. Patients were treated either with a polished tapered Exeter stem or a matte anatomic Lubinus SP12 stem according to the surgeons preference or to the praxis of the present department.

The incidence of perprosthetic femoral fractures Hip-related complications and repeat surgery were assessed at a minimum follow-up of 2 years postoperatively.

Detailed Description

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Conditions

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Femoral Neck Fractures Periprosthetic Fractures

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Lubinus SP2 stem

Patients treated with a cemented Lubinus SP2 stem for a femoral neck fracture. Both total hip arthroplasty and hemiarthroplasty are included.

Lubinus SP2 stem

Intervention Type PROCEDURE

Patients treated with an total or hemiarthroplasty using a SP2stem for a displaced femoral neck fracture

Exeter stem

Patients treated with a cemented Exeter stem for a femoral neck fracture. Both total hip arthroplasty and hemiarthroplasty are included.

Exeter stem

Intervention Type PROCEDURE

Patients treated with an total or hemiarthroplasty using a Exeter stem for a displaced femoral neck fracture

Interventions

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Exeter stem

Patients treated with an total or hemiarthroplasty using a Exeter stem for a displaced femoral neck fracture

Intervention Type PROCEDURE

Lubinus SP2 stem

Patients treated with an total or hemiarthroplasty using a SP2stem for a displaced femoral neck fracture

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Femoral neck fracture
* Treated with hip arthroplasty with Exeter or SP2 stem

Exclusion Criteria

* Patological fracture
* Other typ of stem
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sunderby Hospital

OTHER

Sponsor Role collaborator

Karolinska Institutet

OTHER

Sponsor Role collaborator

Sundsvall Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Inngul C, Enocson A. Postoperative periprosthetic fractures in patients with an Exeter stem due to a femoral neck fracture: cumulative incidence and surgical outcome. Int Orthop. 2015 Sep;39(9):1683-8. doi: 10.1007/s00264-014-2570-0. Epub 2014 Oct 24.

Reference Type BACKGROUND
PMID: 25341951 (View on PubMed)

Mukka S, Mellner C, Knutsson B, Sayed-Noor A, Skoldenberg O. Substantially higher prevalence of postoperative peri-prosthetic fractures in octogenarians with hip fractures operated with a cemented, polished tapered stem rather than an anatomic stem. Acta Orthop. 2016 Jun;87(3):257-61. doi: 10.3109/17453674.2016.1162898. Epub 2016 Apr 4.

Reference Type BACKGROUND
PMID: 27045318 (View on PubMed)

Broden C, Mukka S, Muren O, Eisler T, Boden H, Stark A, Skoldenberg O. High risk of early periprosthetic fractures after primary hip arthroplasty in elderly patients using a cemented, tapered, polished stem. Acta Orthop. 2015 Apr;86(2):169-74. doi: 10.3109/17453674.2014.971388. Epub 2014 Oct 3.

Reference Type BACKGROUND
PMID: 25280133 (View on PubMed)

Mardian S, Perka C, Schaser KD, Gruner J, Scheel F, Schwabe P. Cardiac disease and advanced age increase the mortality risk following surgery for periprosthetic femoral fractures. Bone Joint J. 2017 Jul;99-B(7):921-926. doi: 10.1302/0301-620X.99B7.BJJ-2016-0974.R1.

Reference Type BACKGROUND
PMID: 28663398 (View on PubMed)

Mellner C, Mohammed J, Larsson M, Esberg S, Szymanski M, Hellstrom N, Chang C, Berg HE, Skoldenberg O, Knutsson B, Morberg P, Mukka S. Increased risk for postoperative periprosthetic fracture in hip fracture patients with the Exeter stem than the anatomic SP2 Lubinus stem. Eur J Trauma Emerg Surg. 2021 Jun;47(3):803-809. doi: 10.1007/s00068-019-01263-6. Epub 2019 Nov 18.

Reference Type DERIVED
PMID: 31740996 (View on PubMed)

Other Identifiers

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Multicenter_PPF

Identifier Type: -

Identifier Source: org_study_id

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