Aqueous Urea Concentration May be Related to Cataract Development
NCT ID: NCT03324295
Last Updated: 2018-01-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2017-01-31
2018-07-31
Brief Summary
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Detailed Description
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Asyut University hospitals, Egypt. Three groups of subjects were included:
patients with age related cortical cataracts who are otherwise healthy (cases) and two control groups; first systemically healthy subjects with ocular problems other than cataract and a second control group of patients with impaired renal functions and are not on dialysis treatment and thus have elevated serum urea levels. Slit lamp examination was performed to evaluate crystalline lens for opacities. Measurement of serum urea was done for all study subjects. Aqueous humor urea concentration was done only for the group of patients who are planned to have intraocular surgery. For that purpose, 0.1 ml of aqueous humor will be aspirated at the start of routine intraocular surgery.
Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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cortical cataract
patients with age related cortical cataracts who are otherwise healthy
cortical cataract
Blood urea
ocular problems
systemically healthy subjects with ocular problems other than cataract
cortical cataract
Blood urea
impaired renal functions
patients with impaired renal functions and are not on dialysis
cortical cataract
Blood urea
Interventions
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cortical cataract
Blood urea
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Congenital cataract
* Traumatic cataract
20 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Hassan Lotfy Fahmy
Clinical Professor
Principal Investigators
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Hassan Fahmy, prof
Role: PRINCIPAL_INVESTIGATOR
Assiut University
Locations
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Hassan Lotfy
Asyut, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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IRB000078
Identifier Type: -
Identifier Source: org_study_id
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