Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section
NCT ID: NCT03318536
Last Updated: 2018-05-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
240 participants
OBSERVATIONAL
2017-10-05
2018-02-01
Brief Summary
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Detailed Description
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Due to this fact in our clinic the standard procedure was changed. All patients for caesarean section receive Granisetron before spinal anesthesia.
The aim of the present study is to evaluate the usage and dose of sympathomimetics during spinal anesthesia.
Therefore the investigators will evaluate approximately 120 participants who received granisetron and 120 participants who did not receive 5-hydroxytryptamine 3 receptor antagonists.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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No Granisetron
120 Patients prior to changes of intern standards of caesarean section. Before march 2017 no patient undergoing elective caesarean section received Granisetron as a matter of routine.
No Granisetron
Patients who did not receive Granisetron.
With Granisetron
120 Patients after changes of intern standards of caesarean section. After march 2017 all patient undergoing elective caesarean section received Granisetron as a matter of routine.
Granisetron Hydrochloride
Patients received Granisetron.
Interventions
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Granisetron Hydrochloride
Patients received Granisetron.
No Granisetron
Patients who did not receive Granisetron.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* incomplete documentation
FEMALE
Yes
Sponsors
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Johann Wolfgang Goethe University Hospital
OTHER
Responsible Party
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Dr. med. Florian Raimann
Dr. med. Florian Raimann
Principal Investigators
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Kai Zacharowski, Prof. Dr. med.
Role: STUDY_DIRECTOR
Department of Anesthesia, Intensive Care Medicine and Pain Therapy
Locations
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Klinikum Goethe Universität Frankfurt am Main
Frankfurt am Main, Hesse, Germany
Countries
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References
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Raimann FJ, Baldauf HP, Louwen F, Jennewein L, Fischer D, Zacharowski K, Weber CF. Granisetron reduces the need for uterotonics but not sympathomimetics during cesarean delivery. Int J Gynaecol Obstet. 2019 Jun;145(3):361-366. doi: 10.1002/ijgo.12819. Epub 2019 Apr 15.
Other Identifiers
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XXX/17
Identifier Type: -
Identifier Source: org_study_id
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