Plant Based Diet, Ethnicity, and the Gut Microbiome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-28

Study Completion Date

2019-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Samples will be collected to determine human genetic variation, fecal and oral microbial communities, and metabolome products. Several evolutionary and ecological diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity is less than that between ethnicities; b) if microbiome variation is finely structured according to genetic relatedness; and c) if dietary variation impacts human genome x microbiome associations.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

A Study to Evaluate the Influence of Diet on GI Health

NCT04783142

Healthy

COMPLETED NA

Variability in Microbial Response to Dietary Fiber

NCT06023940

Microbial Colonization

COMPLETED NA

Studies of the Human Microbiome in Clinical Center Patients

NCT01933620

Multidrug-resistant Colonization

ENROLLING_BY_INVITATION

A Novel Fecal Sample Collection Method for Metagenomic Analyses

NCT05172414

Healthy

COMPLETED

Fecal Microbiota Transplant National Registry

NCT03325855

Fecal Microbiota Transplantation Clostridium Difficile Infection Gut Microbiome

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

To characterize the human gut microbiome under highly controlled dietary intake in healthy normal weight adult participants who differ by ethnicity: White non-Hispanic and Black non-Hispanic adults. Samples will be collected to determine human genetic variation, fecal and oral microbial communities, and metabolome products. Several evolutionary and ecological diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity is less than that between ethnicities; b) if microbiome variation is finely structured according to genetic relatedness; and c) if dietary variation impacts human genome x microbiome associations.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diet Modification Microbial Colonization

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Pre Post Design

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Plant Based Diet Group

Study aims for two cohorts of 20 females each, being tested over 6 days in two conditions: habitual diet versus plant based diet.

Group Type EXPERIMENTAL

Plant Based Diet

Intervention Type OTHER

Plant Based Diet for 4 Days Compared to Habitual Diet

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Plant Based Diet

Plant Based Diet for 4 Days Compared to Habitual Diet

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Female
* Age 18-40
* BMI 18.5-24.9
* Caucasian or African American

Exclusion Criteria

* Not weight stable
* Using Medications
* Using Dietary Supplements
* Chronic Disease
* Tobacco Use
* Drug Use
* Pregnant or Lactating
* Diet Restrictions
* Vegetarian or Vegan

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes