HCV Post-Exposure Prophylaxis for Health Care Workers

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Study Start Date

2019-08-13

Study Completion Date

2020-01-16

Brief Summary

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This is an unblinded, observational trial of sofosbuvir-velpatasvir in adult health care workers who are exposed to hepatitis C virus from needlestick injury with hollow-bore needles.

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Detailed Description

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The goal of this study is to assess the safety and tolerability of the use of sofosbuvir-velpatasvir in the setting of post-exposure prophylaxis among Health Care Workers exposed to HCV from needlestick injury with hollow-bore needles

Conditions

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Hepatitis C

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Treatment with Sofosbuvir/Velpatasvir

14 days of treatment with Sofosbuvir/Velpatasvir tablet

Group Type EXPERIMENTAL

Sofosbuvir/Velpatasvir Treatment for 14 days

Intervention Type DRUG

14 day therapy with Sofosbuvir/Velpatasvir

Interventions

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Sofosbuvir/Velpatasvir Treatment for 14 days

14 day therapy with Sofosbuvir/Velpatasvir

Intervention Type DRUG

Other Intervention Names

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Epclusa

Eligibility Criteria

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Inclusion Criteria

* Healthcare worker with exposure through needlestick injury with hollow-bore needles to source patients who are HCV positive
* Healthcare worker must be HCV Ab-