Correlation Between Respiratory Variability of R-R Intervals and Systolic Pressure Variability

NCT ID: NCT03267017

Last Updated: 2017-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-11-01

Study Completion Date

2019-05-01

Brief Summary

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This prospective study is designed to assess and quantify the correlation between respiratory changes in R-R interval and the respiratory changed in invasive systolic blood pressure in ventilated patients during changes in posture and peak end expiratory pressure (PEEP) and following a fluid bolus

Detailed Description

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Conditions

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Heart Rate Determination

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient scheduled for surgery under general anesthesia

posture changes

Intervention Type OTHER

Following induction of general anesthesia and initiation of positive pressure ventilation, patients will be tilted 15 degrees head up for 5 minutes with positive end expiratory pressure of 8 cm H2O, and then 15 degrees head down for 5 minutes with positive end expiratory pressure of 3 cm H2O

Interventions

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posture changes

Following induction of general anesthesia and initiation of positive pressure ventilation, patients will be tilted 15 degrees head up for 5 minutes with positive end expiratory pressure of 8 cm H2O, and then 15 degrees head down for 5 minutes with positive end expiratory pressure of 3 cm H2O

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 18-80
* Scheduled for surgery under general anesthesia requiring invasive blood pressure monitoring

Exclusion Criteria

* Heart Rate other than sinus
* Cardiac Pacemaker Status
* Transplanted Heart
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rambam Health Care Campus

OTHER

Sponsor Role lead

Responsible Party

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Dr. Amit Lehavi MD FANZCA

Director of Pediatric Anesthesia

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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RRV PPV

Identifier Type: -

Identifier Source: org_study_id

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